Alzheimer's disease is the most common type of dementia, being highly prevalent in elderly
women. The advanced progression may be due to decreased hormone synthesis during …

Depletion of estrogens and progesterone at menopause has been linked to an increased
risk for the development of Alzheimer's disease (AD) in women. A currently controversial …

Estrogen depletion in postmenopausal women is a significant risk factor for the development
of Alzheimer's disease (AD), and estrogen-based hormone therapy may reduce this risk …

Depletion of ovarian hormones at menopause is associated with increased Alzheimer's
disease (AD) risk. Hormone loss also increases central adiposity, which promotes AD …

Premenopausal bilateral ovariectomy is considered to be one of the risk factors of
Alzheimer's disease (AD). However, the underlying mechanisms remain unclear. Here, we …

Despite decades of extensive research efforts, efficacious therapies for Alzheimer's disease
(AD) are lacking. The multi-factorial nature of AD neuropathology and symptomatology has …

Abstract Development of Alzheimer's disease (AD) has been linked to the de‐regulation of
estrogen and gonadotropins such as luteinizing hormone (LH). In this study, we found …

Vulnerability to Alzheimer's disease (AD) is increased by several risk factors, including
midlife obesity, female sex, and the depletion of estrogens in women as a consequence of …

Alzheimer's disease (AD) is the most common form of dementia among the elderly with
women exhibiting a higher risk than men for the disease. Due to these gender differences …

Alzheimer's disease (AD) is the leading cause of dementia and has become an important
public health concern. Accumulating evidence indicates that estradiol can both facilitate and …