The role of androgen receptor (AR) activation and expression is well understood in prostate
cancer. In breast cancer, expression and activation of AR is increasingly recognized for its …

The androgen receptor (AR) is a proven clinical target in prostate cancer. Recent research
indicates that it is an emerging hormonal target in breast cancer as well, with potential …

The androgen receptor (AR) is expressed in the majority of breast cancer and across the
three main breast cancer subtypes. Historically, the oncogenic role of AR has best been …

The Androgen Receptor (AR) is emerging as an important factor in the pathogenesis of
breast cancer (BC), which is the most common malignancy among females worldwide. The …

Breast cancer occurs at a high frequency in women and, given this fact, a primary focus of
breast cancer research has been the study of estrogen receptor α (ER) signaling. However …

Importance The androgen receptor (AR) pathway is emerging as a potential therapeutic
target in breast cancer. To date, AR-targeted drugs have been approved only for treatment of …

Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Androgen receptor (AR) signaling exerts an antiestrogenic, growth-inhibitory influence in
normal breast tissue, and this role may be sustained in estrogen receptor α (ERα)-positive …

Molecular and histopathological profiling have classified breast cancer into multiple sub-
types empowering precision treatment. Although estrogen receptor (ER) and human …

The androgen receptor (AR) is a ligand-dependent transcription factor, and its effects on
breast range from physiological pubertal development and age-related modifications to …