Abstract Background Systematic reviews (SRs) are the highest form of evidence for all types
of clinical questions in evidence-based practice. For the first time in 2018, the number of SRs …

Background. Participant withdrawal from clinical trials occurs for various reasons,
predominantly adverse effects or intervention inefficacy. Because these missing participant …

Systematic reviews (SRs) of the literature are clinical research studies carried out according
to rigorous methodological criteria. They are aimed at searching, critically appraising and …

Background Although advances in treatment have dramatically improved short-term graft
survival and acute rejection in kidney transplant recipients, long-term graft outcomes have …

Background The potential for clinical trials to impact patient care may be limited if the
outcomes reported vary by trial and lack direct relevance to patients. Despite the many trials …

Physicians often scan a select number of journals to keep up to date with practice evidence
for patients with kidney conditions. This raises the question of where relevant studies are …

Background Although clinical practice guidelines (CPGs) are used for the development of
local protocols in kidney transplantation (Ktx), the quality of their methodology is variable …

Background. Uncertainties about best management of end‐stage renal disease (ESRD) are
reflected in wide variations in practice. Systematic reviews aim to reduce uncertainty by …

It has been 20 years since the Cochrane Collaboration started the global effort to synthesize
evidence to improve healthcare. Since 1997, the Cochrane Renal Group has produced over …

Randomized controlled trials (RCTs) of interventions provide the highest level of evidence
about efficacy but their value either alone or within a meta‐analysis is dependent on its …