Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer

JJG Marin, F Sanchez de Medina… - Drug metabolism …, 2012 - Taylor & Francis
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death in industrialized countries. Chemoprevention is a promising approach …

Epidemiology, treatment and chemoprevention in colorectal cancer

P Rougier, E Mitry - Annals of Oncology, 2003 - Elsevier
In Western countries, colorectal cancer (CRC) is second only to cancer of the lung as a
cause of death from malignancy, and affects perhaps one in 20 of the population. In the pre …

Colorectal cancer chemoprevention: biochemical targets and clinical development of promising agents

RA Sharma, MM Manson, A Gescher… - European Journal of …, 2001 - Elsevier
Colorectal cancer (CRC) remains a cause of significant mortality in developed countries
despite extensive knowledge of its epidemiology and molecular basis. Since multiple …

Cellular mechanisms accounting for the refractoriness of colorectal carcinoma to pharmacological treatment

JJG Marin, RIR Macias, MJ Monte, E Herraez… - Cancers, 2020 - mdpi.com
Simple Summary Colorectal cancer (CRC) causes a high number (more than 800,000) of
deaths worldwide each year. Better methods for early diagnosis and the development of …

Chemoprevention for colorectal cancer

K Krishnan, MT Ruffin IV, DE Brenner - Critical reviews in oncology …, 2000 - Elsevier
Colon cancer is the second most common malignancy in the developed world with an
estimated 94 100 new cases and 46600 deaths in the United States in 1997 [1]. Americans …

Colon cancer: preventive agents and the present status of chemoprevention

E Half, N Arber - Expert opinion on pharmacotherapy, 2009 - Taylor & Francis
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide and a
prevalent cause of morbidity and mortality. CRC has a natural history of transition from a …

Chemoprevention of colorectal cancer

R Raju, M Cruz-Correa - Diseases of the colon & rectum, 2006 - journals.lww.com
Colorectal cancer is a major public health concern in all developed countries. Despite
decades of advances in the treatment and prevention of colorectal cancer, it remains the …

Chemoprevention of colorectal cancer: ready for routine use?

N Arber, B Levin - Current Topics in Medicinal Chemistry, 2005 - ingentaconnect.com
In the third millennium preventive medicine is becoming a corner stone in our concept of
health. Colorectal cancer (CRC) prevention, in particular, has become an important goal for …

Chemoprevention of colorectal cancer: Past, present, and future

S Umezawa, T Higurashi, Y Komiya, J Arimoto… - Cancer …, 2019 - Wiley Online Library
Chemoprevention began to be considered as a potential strategy for lowering the incidence
of cancer and cancer‐related deaths in the 1970s. For clinical chemoprevention trials …

Chemoprevention of colorectal cancer

EDJ Courtney, DM Melville… - Alimentary …, 2004 - Wiley Online Library
Colorectal cancer is a disease with a high mortality at present, due to the late stage at which
many cases present. Attention is therefore focusing on preventative strategies for colorectal …