Natural compounds have shown good potential for the discovery of new chemotherapeutics
for the treatment of Chagas' disease. Recently, our group reported the effective trypanocidal …

Chagas' disease, a vector-transmitted infectious disease, is caused by the protozoa parasite
Trypanosoma cruzi. Drugs that are currently available for the treatment of this disease are …

Chagas' disease is a debilitating but comparatively neglected illness that affects about 15
million people. There is an urgent need to develop new, more effective, and less-toxic …

Natural marine products have shown an interesting array of diverse and novel chemical
structures with potent biological activities. Our study reports the antiproliferative assays of …

Background Leishmaniasis, a parasitic disease caused by protozoa of the genus
Leishmania, affects more than 12 million people worldwide. Quercetin has generated …

Background Deoxymikanolide is a sesquiterpene lactone isolated from Mikania micrantha
and M. variifolia which, has previously demonstrated in vitro activity on Trypanosoma cruzi …

Leishmaniasis is an important neglected disease caused by protozoa of the genus
Leishmania that affects more than 12 million people worldwide. Leishmaniasis treatment …

Over the past years, natural products have been explored in order to find biological active
substances to treat various diseases. Regarding their potential action against parasites such …

Introduction Chagas disease, caused by the protozoan parasiteTrypanosoma cruzi, has no
effective treatment available. On the other hand, microalgae are aquatic organisms that …

The MeOH extract from leaves of Saururus cernuus L.(Saururaceae) displayed in vitro
activity against trypomastigote forms of T. cruzi (100% of parasite death at 200 μg/mL) …