Recent Advances in 64Cu/67Cu-Based Radiopharmaceuticals

OO Krasnovskaya, D Abramchuck, A Erofeev… - International Journal of …, 2023 - mdpi.com
Copper-64 (T1/2= 12.7 h) is a positron and beta-emitting isotope, with decay characteristics
suitable for both positron emission tomography (PET) imaging and radiotherapy of cancer …

64Cu-based Radiopharmaceuticals in Molecular Imaging

Y Zhou, J Li, X Xu, M Zhao, B Zhang… - … in cancer research & …, 2019 - journals.sagepub.com
Copper-64 (T1/2= 12.7 hours; β+: 19%, β−: 38%) has a unique decay profile and can be
used for positron emission tomography imaging and radionuclide therapy. The well …

Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research

CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …

Recent advances in copper radiopharmaceuticals

G Hao, AN Singh, OK Oz, X Sun - Current …, 2011 - ingentaconnect.com
Copper has five radioisotopes (60Cu, 61Cu, 62Cu, 64Cu, and 67Cu) that can be used in
copper radiopharmaceuticals. These radioisotopes decay by mixed emissions of β+, β-, and …

Copper-64: a real theranostic agent

B Gutfilen, SAL Souza, G Valentini - Drug design, development and …, 2018 - Taylor & Francis
Ongoing studies of physiological and pathological processes have led to a corresponding
need for new radiopharmaceuticals, especially when studies are limited by the absence of a …

Copper chelation chemistry and its role in copper radiopharmaceuticals

TJ Wadas, EH Wong, GR Weisman… - Current …, 2007 - ingentaconnect.com
Molecular imaging is an important scientific discipline that plays a major role in clinical
medicine and pharmaceutical development. While several imaging modalities including X …

The emerging role of copper-64 radiopharmaceuticals as cancer theranostics

A Boschi, P Martini, E Janevik-Ivanovska, A Duatti - Drug Discovery Today, 2018 - Elsevier
Highlights•Copper radionuclides for in vivo imaging of biological functions of copper
ions.•Copper-64 has suitable nuclear properties for cancer theranostics.•Radioactive copper …

Copper radionuclides for theranostic applications: towards standardisation of their nuclear data. A mini-review

M Hussain, SM Qaim, I Spahn, MN Aslam… - Frontiers in …, 2023 - frontiersin.org
Copper has several clinically relevant radioisotopes and versatile coordination chemistry,
allowing attachment of its radionuclides to biological molecules. This characteristic makes it …

[PDF][PDF] The current status and future of theranostic Copper-64 radiopharmaceuticals

AR Jalilian, J Osso Jr - Iranian Journal of Nuclear Medicine, 2017 - irjnm.tums.ac.ir
Copper-64 was produced in large scales and high specific activities in late 1990s' using
compact cyclotrons based by 64Ni (p, n) 64Cu reaction and many radiopharmaceuticals …

Reactor produced [64Cu]CuCl2 as a PET radiopharmaceutical for cancer imaging: from radiochemistry laboratory to nuclear medicine clinic

R Chakravarty, P Shetty, KVV Nair, A Rajeswari… - Annals of Nuclear …, 2020 - Springer
Objective Copper-64 is a useful theranostic radioisotope that is attracting renewed interest
from the nuclear medicine community in the recent times. This study aims to demonstrate the …