Sagittal craniosynostosis is the most common form of craniosynostosis, affecting
approximately one in 5,000 newborns. We conducted, to our knowledge, the first genome …

Our previous genome-wide association study (GWAS) for sagittal nonsyndromic
craniosynostosis (sNCS) provided important insights into the genetics of midline CS. In this …

Premature fusion of the cranial sutures (craniosynostosis), affecting 1 in 2000 newborns, is
treated surgically in infancy to prevent adverse neurologic outcomes. To identify mutations …

Non-syndromic craniosynostosis (NSC) is a frequent congenital malformation in which one
or more cranial sutures fuse prematurely. Mutations causing rare syndromic …

Lambdoid craniosynostosis (CS) is a congenital anomaly resulting from premature fusion of
the cranial suture between the parietal and occipital bones. Predominantly sporadic, it is the …

Craniosynostosis describes conditions in which one or more sutures of the infant skull are
prematurely fused, resulting in facial deformity and delayed brain development …

We describe a family that segregated an autosomal dominant form of craniosynostosis
characterized by variable expression and limited extra‐cranial features. Linkage analysis …

Bone morphogenetic protein 2 (BMP2) in chromosomal region 20p12 belongs to a gene
superfamily encoding TGF-β-signaling proteins involved in bone and cartilage biology …

Background: Craniosynostosis is a condition that includes the premature fusion of one or
multiple cranial sutures. Among various craniosynostosis forms, sagittal nonsyndromic …

Craniosynostosis, the premature ossification of cranial sutures, is a developmental disorder
of the skull vault, occurring in approximately 1 in 2250 births. The causes are …