The intersection of metformin and inflammation
LP Bharath, BS Nikolajczyk - American Journal of …, 2021 - journals.physiology.org
The biguanide metformin is the most commonly used antidiabetic drug. Recent studies show
that metformin not only improves chronic inflammation by improving metabolic parameters …
that metformin not only improves chronic inflammation by improving metabolic parameters …
Metformin, a new era for an old drug in the treatment of immune mediated disease?
M Schuiveling, N Vazirpanah… - Current drug …, 2018 - ingentaconnect.com
Background: Metformin, a widely prescribed blood glucose normalizing antidiabetic drug, is
now beginning to receive increasing attention due to its anti-inflammatory properties …
now beginning to receive increasing attention due to its anti-inflammatory properties …
[HTML][HTML] Metformin as an anti-inflammatory agent: a short review
R Kristófi, JW Eriksson - Journal of Endocrinology, 2021 - joe.bioscientifica.com
Metformin is a biguanide drug widely used as the initial treatment of type 2 diabetes. Despite
its widespread use, its precise mechanisms of action remain incompletely characterised. Its …
its widespread use, its precise mechanisms of action remain incompletely characterised. Its …
Metformin and inflammation: its potential beyond glucose-lowering effect
Y Saisho - Endocrine, Metabolic & Immune Disorders-Drug …, 2015 - ingentaconnect.com
Metformin is an oral hypoglycemic agent which is most widely used as first-line therapy for
type 2 diabetes. Metformin improves hyperglycemia by suppressing hepatic glucose …
type 2 diabetes. Metformin improves hyperglycemia by suppressing hepatic glucose …
[HTML][HTML] Metformin: a novel weapon against inflammation
B Bai, H Chen - Frontiers in pharmacology, 2021 - frontiersin.org
It has become widely accepted that inflammation is a driving force behind a variety of
chronic diseases, such as cardiovascular disease, diabetes, kidney disease, cancer …
chronic diseases, such as cardiovascular disease, diabetes, kidney disease, cancer …
An update on mode of action of metformin in modulation of meta-inflammation and inflammaging
M Khodadadi, D Jafari-Gharabaghlou… - Pharmacological …, 2022 - Springer
Type 2 diabetes mellitus (T2DM) is the most common chronic metabolic condition. Several
genetic and environmental factors are involved in developing T2DM. Aging, inflammation …
genetic and environmental factors are involved in developing T2DM. Aging, inflammation …
[引用][C] Pleiotropic benefits of metformin: macrophage targeting its anti-inflammatory mechanisms
Y Hattori, K Hattori, T Hayashi - Diabetes, 2015 - Am Diabetes Assoc
Metformin is a biguanide family member used in the treatment of type 2 diabetes and one of
the most widely prescribed antidiabetes drugs. This drug increases the peripheral uptake of …
the most widely prescribed antidiabetes drugs. This drug increases the peripheral uptake of …
New mechanisms of metformin action: Focusing on mitochondria and the gut
KY Hur, MS Lee - Journal of diabetes investigation, 2015 - Wiley Online Library
The most well‐known mechanism of metformin action, one of the most commonly prescribed
antidiabetic drugs, is adenosine monophosphate‐activated protein kinase activation; …
antidiabetic drugs, is adenosine monophosphate‐activated protein kinase activation; …
Role of metformin in inflammation
YY Feng, Z Wang, H Pang - Molecular biology reports, 2023 - Springer
Background Metformin has good anti-hyperglycemic effectiveness, but does not induce
hypoglycemia, is very safe, and has become the preferred drug for the treatment of type 2 …
hypoglycemia, is very safe, and has become the preferred drug for the treatment of type 2 …
[HTML][HTML] Metformin and autoimmunity: a “new deal” of an old drug
Metformin (dimethyl biguanide) is a synthetic derivative of guanidine, isolated from the
extracts of Galega officinalis, a plant with a prominent antidiabetic effect. Since its discovery …
extracts of Galega officinalis, a plant with a prominent antidiabetic effect. Since its discovery …