Endocrine functions of the heart: from bench to bedside

M Volpe, G Gallo, S Rubattu - European Heart Journal, 2023 - academic.oup.com
Heart has a recognized endocrine function as it produces several biologically active
substances with hormonal properties. Among these hormones, the natriuretic peptide (NP) …

Natriuretic peptides: it is time for guided therapeutic strategies based on their molecular mechanisms

G Gallo, S Rubattu, C Autore, M Volpe - International Journal of Molecular …, 2023 - mdpi.com
Natriuretic peptides (NPs) are the principal expression products of the endocrine function of
the heart. They exert several beneficial effects, mostly mediated through guanylate cyclase …

The natriuretic peptides system in the pathophysiology of heart failure: from molecular basis to treatment

M Volpe, M Carnovali, V Mastromarino - Clinical Science, 2016 - portlandpress.com
After its discovery in the early 1980s, the natriuretic peptide (NP) system has been
extensively characterized and its potential influence in the development and progression of …

Natriuretic peptides: molecular biology, pathophysiology and clinical implications for the cardiologist

RD 'Alessandro, D Masarone, A Buono… - Future …, 2013 - Taylor & Francis
Natriuretic peptides (NPs) counter the effects of volume overload or adrenergic activation of
the cardiovascular system. They are able to induce arterial vasodilatations, natriuresis and …

The importance of natriuretic peptides in cardiometabolic diseases

S Vinnakota, HH Chen - Journal of the Endocrine Society, 2020 - academic.oup.com
The natriuretic peptide (NP) system is composed of 3 distinct peptides (atrial natriuretic
peptide or ANP, B-type natriuretic peptide or BNP, and C-type natriuretic peptide or CNP) …

Natriuretic peptides in the cardiovascular system: multifaceted roles in physiology, pathology and therapeutics

S Rubattu, M Volpe - International Journal of Molecular Sciences, 2019 - mdpi.com
The natriuretic peptides (NPs) family includes a class of hormones and their receptors
needed for the physiological control of cardiovascular functions. The discovery of NPs …

Natriuretic peptides in heart failure: Current achievements and future perspectives

M Volpe, A Battistoni, S Rubattu - International journal of cardiology, 2019 - Elsevier
The last two centuries have witnessed countless discoveries in the field of medicine that
found their roots in the up growing development of technology as well as in the visionary …

[HTML][HTML] Natriuretic peptides and cardio-renal disease

M Volpe - International journal of cardiology, 2014 - Elsevier
The natriuretic peptide (NP) system is an important endocrine, autocrine and paracrine
system, consisting of a family of peptides which provide cardiac, renal and vascular effects …

Natriuretic peptide system and cardiovascular disease

F Cacciapuoti - Heart views, 2010 - journals.lww.com
Abstract The mammalian Natriuretic Peptide (NP) system consists of neuro-hormones, such
as atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), c-type natriuretic peptide …

Natriuretic peptides: an update on bioactivity, potential therapeutic use, and implication in cardiovascular diseases

S Rubattu, S Sciarretta, V Valenti… - American journal of …, 2008 - academic.oup.com
The natriuretic peptide system includes three known peptides: atrial natriuretic peptide
(ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). They contribute …