Patient-reported outcomes during and after treatment for locally advanced rectal cancer in the PROSPECT trial (Alliance N1048)
E Basch, AC Dueck, SA Mitchell, H Mamon… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The standard of care for locally advanced rectal cancer in North America is
neoadjuvant pelvic chemoradiation with fluorouracil (5FUCRT). Neoadjuvant chemotherapy …
neoadjuvant pelvic chemoradiation with fluorouracil (5FUCRT). Neoadjuvant chemotherapy …
Preoperative treatment of locally advanced rectal cancer
D Schrag, Q Shi, MR Weiser, MJ Gollub… - … England Journal of …, 2023 - Mass Medical Soc
Background Pelvic radiation plus sensitizing chemotherapy with a fluoropyrimidine
(chemoradiotherapy) before surgery is standard care for locally advanced rectal cancer in …
(chemoradiotherapy) before surgery is standard care for locally advanced rectal cancer in …
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: 7-year results of PRODIGE 23 …
LBA3504 Background: We have reported that neoadjuvant chemotherapy (NACT) with
FOLFIRINOX followed by chemoradiotherapy (CRT), surgery, and adjuvant chemotherapy …
FOLFIRINOX followed by chemoradiotherapy (CRT), surgery, and adjuvant chemotherapy …
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: final results of PRODIGE 23 phase …
T Conroy, N Lamfichekh, PL Etienne, E Rio, E Francois… - 2020 - ascopubs.org
4007 Background: PRODIGE 23 investigated the role of neoadjuvant mFOLFIRINOX before
preoperative (preop) chemoradiation (CRT), with TME-surgery and adjuvant chemotherapy …
preoperative (preop) chemoradiation (CRT), with TME-surgery and adjuvant chemotherapy …
Neoadjuvant chemotherapy first, followed by chemoradiation and then surgery, in the management of locally advanced rectal cancer
A Cercek, KA Goodman, C Hajj, E Weisberger… - Journal of the National …, 2014 - jnccn.org
Standard therapy for locally advanced rectal cancer (LARC) is preoperative
chemoradiotherapy and postoperative chemotherapy. At Memorial Sloan-Kettering Cancer …
chemoradiotherapy and postoperative chemotherapy. At Memorial Sloan-Kettering Cancer …
Neoadjuvant modified FOLFOX6 with or without radiation versus fluorouracil plus radiation for locally advanced rectal cancer: final results of the Chinese FOWARC …
Y Deng, P Chi, P Lan, L Wang, W Chen… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE In the multicenter, open-label, phase III FOWARC trial, modified infusional
fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus radiotherapy resulted in a higher …
fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus radiotherapy resulted in a higher …
Complete neoadjuvant treatment for rectal cancer: the Brown University Oncology Group CONTRE Study
K Perez, H Safran, W Sikov, M Vrees… - American journal of …, 2017 - journals.lww.com
Purpose: Following preoperative chemoradiation and surgery, many patients with stage II to
III rectal cancer are unable to tolerate full-dose adjuvant chemotherapy. BrUOG R-224 was …
III rectal cancer are unable to tolerate full-dose adjuvant chemotherapy. BrUOG R-224 was …
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized …
C Aschele, L Cionini, S Lonardi, C Pinto… - Journal of clinical …, 2011 - ascopubs.org
Purpose To investigate oxaliplatin combined with fluorouracil-based chemoradiotherapy as
preoperative treatment for locally advanced rectal cancer. Patients and Methods Seven …
preoperative treatment for locally advanced rectal cancer. Patients and Methods Seven …
Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a …
T Conroy, JF Bosset, PL Etienne, E Rio… - The Lancet …, 2021 - thelancet.com
Background Treatment of locally advanced rectal cancer with chemoradiotherapy, surgery,
and adjuvant chemotherapy controls local disease, but distant metastases remain common …
and adjuvant chemotherapy controls local disease, but distant metastases remain common …
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial …
Background Preoperative chemoradiotherapy, total mesorectal excision surgery, and
adjuvant chemotherapy with fluorouracil is the standard combined modality treatment for …
adjuvant chemotherapy with fluorouracil is the standard combined modality treatment for …