CXCR3 ligands: redundant, collaborative and antagonistic functions
JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
CXCR3 in T cell function
JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
[HTML][HTML] Overview of the mechanisms that may contribute to the non-redundant activities of interferon-inducible CXC chemokine receptor 3 ligands
M Metzemaekers, V Vanheule, R Janssens… - Frontiers in …, 2018 - frontiersin.org
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …
The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor
The chemokine receptor CXCR3 is expressed on the surface of both resting and activated T
lymphocytes. We describe in this study the endocytosis of CXCR3 using T lymphocytes and …
lymphocytes. We describe in this study the endocytosis of CXCR3 using T lymphocytes and …
CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis
RA Colvin, GSV Campanella, LA Manice… - Molecular and cellular …, 2006 - Taylor & Francis
CXCR3 is a G-protein-coupled seven-transmembrane domain chemokine receptor that
plays an important role in effector T-cell and NK cell trafficking. Three gamma interferon …
plays an important role in effector T-cell and NK cell trafficking. Three gamma interferon …
Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi‐step model of ligand binding …
G Xanthou, TJ Williams… - European journal of …, 2003 - Wiley Online Library
CXCR3 is a chemokine receptor predominantly expressed on T lymphocytes, and binds the
chemokines CXCL9 (Mig), CXCL10 (IP‐10) and CXCL11 (I‐TAC). Here, we have …
chemokines CXCL9 (Mig), CXCL10 (IP‐10) and CXCL11 (I‐TAC). Here, we have …
Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation
JH Xie, N Nomura, M Lu, SL Chen… - Journal of leucocyte …, 2003 - academic.oup.com
Naïve T cells, when activated by specific antigen and cytokines, up-regulate adhesion
molecules as well as chemokine receptors on their surface, which allows them to migrate to …
molecules as well as chemokine receptors on their surface, which allows them to migrate to …
[HTML][HTML] Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function
RA Colvin, GSV Campanella, J Sun… - Journal of Biological …, 2004 - ASBMB
The chemokine receptor CXCR3 is a G protein-coupled receptor found predominantly on T
cells that is activated by three ligands as follows: CXCL9 (Mig), CXCL10 (IP-10), and …
cells that is activated by three ligands as follows: CXCL9 (Mig), CXCL10 (IP-10), and …
[HTML][HTML] Diversity and inter-connections in the CXCR4 chemokine receptor/ligand family: molecular perspectives
L Pawig, C Klasen, C Weber, J Bernhagen… - Frontiers in …, 2015 - frontiersin.org
CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow
and their recruitment to sites of injury, as well as affect processes such as cell arrest …
and their recruitment to sites of injury, as well as affect processes such as cell arrest …
Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer
MW Nasser, SK Raghuwanshi, DJ Grant… - The Journal of …, 2009 - journals.aai.org
CXCL8 (also known as IL-8) activates CXCR1 and CXCR2 to mediate neutrophil recruitment
and trigger cytotoxic effect at sites of infection. Under physiological conditions, CXCL8 could …
and trigger cytotoxic effect at sites of infection. Under physiological conditions, CXCL8 could …