The projected effect of risk factor reduction on Alzheimer's disease prevalence

DE Barnes, K Yaffe - The Lancet Neurology, 2011 - thelancet.com
Summary At present, about 33· 9 million people worldwide have Alzheimer's disease (AD),
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

S Norton, FE Matthews, DE Barnes, K Yaffe… - The Lancet …, 2014 - thelancet.com
Background Recent estimates suggesting that over half of Alzheimer's disease burden
worldwide might be attributed to potentially modifiable risk factors do not take into account …

Prevention of cognitive decline in ageing: dementia as the target, delayed onset as the goal

L Fratiglioni, C Qiu - The Lancet Neurology, 2011 - thelancet.com
Less than two decades have passed since the first incidence data for Alzheimer's disease
(AD) and other dementias were reported, during which there have been many achievements …

Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions

S Andrieu, N Coley, S Lovestone, PS Aisen… - The Lancet …, 2015 - thelancet.com
Interventions that have even quite modest effects at the individual level could drastically
reduce the future burden of dementia associated with Alzheimer's disease at the population …

[HTML][HTML] Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study …

E Nichols, CEI Szoeke, SE Vollset, N Abbasi… - The Lancet …, 2019 - thelancet.com
Background The number of individuals living with dementia is increasing, negatively
affecting families, communities, and health-care systems around the world. A successful …

Alzheimer's disease

P Scheltens, B De Strooper, M Kivipelto, H Holstege… - The Lancet, 2021 - thelancet.com
In this Seminar, we highlight the main developments in the field of Alzheimer's disease. The
most recent data indicate that, by 2050, the prevalence of dementia will double in Europe …

Alzheimer's disease

C Ballard, S Gauthier, A Corbett, C Brayne, D Aarsland… - the Lancet, 2011 - thelancet.com
An estimated 24 million people worldwide have dementia, the majority of whom are thought
to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health …

The age gap between patients in clinical studies and in the general population: a pitfall for dementia research

N Schoenmaker, WA Van Gool - The Lancet Neurology, 2004 - thelancet.com
Summary The growing global disease burden attributable to dementia has strongly
stimulated research activities. However, patients with dementia that are included in clinical …

Making Alzheimer's and dementia research fit for populations

C Brayne, D Davis - The Lancet, 2012 - thelancet.com
Two decades ago, the established view was that ageing and Alzheimer's disease arise from
distinct pathophysiological processes. Tremendous scientific efforts were underway to …

Alzheimer's disease

P Scheltens, K Blennow, MMB Breteler, B De Strooper… - The Lancet, 2016 - thelancet.com
Although the prevalence of dementia continues to increase worldwide, incidence in the
western world might have decreased as a result of better vascular care and improved brain …