Phosphodiesterase type 5 inhibitors for the treatment of sexual dysfunction in males with major depressive disorder: A systematic review and meta‐analysis.

K Sakuma, T Kishi, S Sanji, I Nomura… - Psychiatry & …, 2023 - search.ebscohost.com
Both pooled PDE5-Is and individual PDE5-Is (sildenafil and vardenafil) outperformed the
placebo in the improvement of all IIEF domain scores. A recent meta-analysis recommended …

Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient

G Corona, N Mondaini, A Ungar… - The Journal of …, 2011 - academic.oup.com
Introduction Erectile dysfunction (ED) is a very common multidimensional disorder affecting
men worldwide. Physical illness, reaction to life stresses, or an unhappy couple relationship …

Treating erectile dysfunction and central neurological diseases with oral phosphodiesterase type 5 inhibitors. Review of the literature

G Lombardi, F Nelli, M Celso… - The Journal of …, 2012 - academic.oup.com
Introduction Erectile dysfunction (ED) is reported in a high percentage of patients with
central neurological disorders (CND). Aim An up-to-date review on oral phosphodiesterase …

Sexual Psychopharmacology: Important Symptomatic Treatment in Depression and Anxiety?

RH Belmaker, P Lichtenberg - … : A Concise Guide Exploring the Limits of …, 2023 - Springer
Sexual dysfunction is an important part of symptomatology in depression and anxiety and
can be a serious side effect of treatment of depression or psychosis. PDE-5 inhibitor …

PDE-5 inhibition and sexual response: pharmacological mechanisms and clinical outcomes

RC Rosen, KE McKenna - Annual review of sex research, 2002 - Taylor & Francis
Abstract Phosphodiesterase type-5 (PDE-5) inhibitors are a new class of vasoactive drugs
that have been developed for treatment of erectile dysfunction (ED). The mechanism of …

Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysis

A Tsertsvadze, HA Fink, F Yazdi… - Annals of internal …, 2009 - acpjournals.org
Background: Erectile dysfunction (ED) is a common male sexual disorder. The relative
benefits and harms of pharmacologic therapies for ED, as well as the value of hormonal …

Phosphodiesterase type 5 inhibitor therapy: identifying and exploring what attributes matter more to clinicians and patients in the management of erectile dysfunction

AC Axilrod - Current medical research and opinion, 2007 - Taylor & Francis
Background: Erectile dysfunction (ED) is increasingly being recognized as a sentinel marker
of future subsequent cardiovascular disease (CVD). Predicted increases in the prevalence …

Which is first? The controversial issue of precedence in the treatment of male sexual dysfunctions

EA Jannini, AM Isidori, A Aversa… - The Journal of Sexual …, 2013 - academic.oup.com
Introduction In male sexual dysfunction (MSD), the presence of sexual comorbidities is
relatively frequent. However, what is still a matter of controversy is what the first‐line therapy …

Prescribing PDE5 Inhibitors: Best Practices, Common Practices, and Controversies

MR Klein, AW Shindel - Current Sexual Health Reports, 2023 - Springer
Abstract Purpose of Review Erectile dysfunction (ED) is an increasingly common concern
that has been a topic of interest to men (and their partners) since time immemorial. In the …

How to evaluate the efficacy of the phosphodiesterase type 5 inhibitors

EA Jannini, LR DeRogatis, E Chung… - The Journal of Sexual …, 2012 - academic.oup.com
Introduction Several methods have been so far proposed to compare the effectiveness of the
three available phosphodiesterase type 5 inhibitors (PDE5Is). Methods Two urologists (EC …