Transcriptomic analysis of Porphyromonas gingivalis‐infected head and neck cancer cells: Identification of PLAU as a candidate prognostic biomarker
M Hamada, H Inaba, K Nishiyama… - Journal of Cellular …, 2024 - Wiley Online Library
Periodontal disease is a risk factor for head and neck squamous cell carcinoma (HNSCC),
and Porphyromonas gingivalis, a major periodontal pathogen, has been identified as a …
and Porphyromonas gingivalis, a major periodontal pathogen, has been identified as a …
[HTML][HTML] Overexpressed PLAU and its potential prognostic value in head and neck squamous cell carcinoma
Z Li, C Chen, J Wang, M Wei, G Liu, Y Qin, L She, Y Liu… - PeerJ, 2021 - peerj.com
Background Metastasis is a major event for survival and prognosis in patients with head and
neck squamous cell carcinomas (HNSCC). A primary cause of metastasis is the proteolytic …
neck squamous cell carcinomas (HNSCC). A primary cause of metastasis is the proteolytic …
[HTML][HTML] Distinct gene expression characteristics in epithelial cell-Porphyromonas gingivalis interactions by integrating transcriptome analyses
D Zhang, J Hou, Y Wu, Y Liu, R Li, T Xu… - International Journal of …, 2019 - ncbi.nlm.nih.gov
Porphyromonas gingivalis is a pivotal periodontal pathogen, and the epithelial cells serve as
the first physical barrier to defend the host from bacterial attack. Within this host-bacteria …
the first physical barrier to defend the host from bacterial attack. Within this host-bacteria …
[HTML][HTML] Identification of Potential Candidate Genes of Oral Cancer in Response to Chronic Infection With Porphyromonas gingivalis Using Bioinformatical Analyses
F Geng, Q Wang, C Li, J Liu, D Zhang, S Zhang… - Frontiers in …, 2019 - frontiersin.org
Recent investigations revealed the relationship between chronic periodontitis,
Porphyromonas gingivalis and cancer. However, host genes that change in response to …
Porphyromonas gingivalis and cancer. However, host genes that change in response to …
[HTML][HTML] Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck …
Z Huo, X Li, J Zhou, Y Fan, Z Wang, Z Zhang - Cancer cell international, 2021 - Springer
Background DNA methylation and miRNA-target genes play an important part in the early
development of various tumors and have been studied as tumor biomarkers. Although …
development of various tumors and have been studied as tumor biomarkers. Although …
[HTML][HTML] PLAU promotes cell proliferation and epithelial-mesenchymal transition in head and neck squamous cell carcinoma
G Chen, J Sun, M Xie, S Yu, Q Tang, L Chen - Frontiers in genetics, 2021 - frontiersin.org
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation
is often accompanied by various cancers. However, the biological functions and potential …
is often accompanied by various cancers. However, the biological functions and potential …
[HTML][HTML] Potentially novel candidate biomarkers for head and neck squamous cell carcinoma identified using an integrated cell line-based discovery strategy
L Sepiashvili, A Hui, V Ignatchenko, W Shi, S Su… - Molecular & Cellular …, 2012 - ASBMB
Head and neck squamous cell carcinomas (HNSCC) can arise from the oral cavity,
oropharynx, larynx or hypopharynx, and is the sixth leading cancer by incidence worldwide …
oropharynx, larynx or hypopharynx, and is the sixth leading cancer by incidence worldwide …
PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway
X Cui, H Sun, X Liu, Y Bai, Y Bai, Y Cui, B Wang… - Experimental Cell …, 2024 - Elsevier
It was reported that within the head and neck cancer (HNC) cell line CAL21 the epithelial-
mesenchymal transition (EMT) and cell proliferation were promoted by Urokinase-Type …
mesenchymal transition (EMT) and cell proliferation were promoted by Urokinase-Type …
[HTML][HTML] Bioinformatics and immunohistochemistry analyses of expression levels and clinical significance of CXCL2 and TANs in an oral squamous cell carcinoma …
ZC Guo, S Jumatai, SL Jing, LL Hu… - Oncology …, 2021 - spandidos-publications.com
The present study aimed to detect the immunoexpression and clinical significance of
Porphyromonas gingivalis (P. gingivalis) in the tumor microenvironment (TME) of oral …
Porphyromonas gingivalis (P. gingivalis) in the tumor microenvironment (TME) of oral …
[HTML][HTML] PLAU and LAMC2 can predict a poor prognosis in patients with HNSCC
Z Guo, S Jing, H Cui, L Xie, S Na, J Tu - Journal of Cancer, 2023 - ncbi.nlm.nih.gov
Objectives: Head and neck squamous cell carcinoma (HNSCC) is the most common
malignancy of the head and neck. However, the molecular mechanisms governing the …
malignancy of the head and neck. However, the molecular mechanisms governing the …