Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation‐Positive Non‐Small Cell Lung Cancer: A Prospective, Single‐Arm, Phase II Study

L Xiong, R Li, J Sun, Y Lou, W Zhang, H Bai… - The …, 2019 - academic.oup.com
Abstract Lessons Learned The findings of this prospective, single‐arm, phase II study
showed that neoadjuvant erlotinib was well tolerated and might improve the radical …

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE To assess the benefits of epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors as neoadjuvant/adjuvant therapies in locally advanced EGFR mutation …

[HTML][HTML] Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

H Zhai, W Zhong, X Yang, YL Wu - Translational lung cancer …, 2015 - ncbi.nlm.nih.gov
Abstract The Lung Adjuvant Cisplatin Evaluation (LACE) meta-analysis and the meta-
analysis of individual participant data reported by non-small cell lung cancer (NSCLC) Meta …

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the …

WZ Zhong, HH Yan, KN Chen, C Chen… - Signal transduction and …, 2023 - nature.com
EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with
neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations …

Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients

L Xiong, Y Lou, H Bai, R Li, J Xia… - Journal of …, 2020 - journals.sagepub.com
Background The optimal neoadjuvant regimen for locally advanced resectable non-small
cell lung cancer (NSCLC) remains controversial. EGFR inhibitors have significantly …

Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status

W Zhong, X Yang, H Yan, X Zhang, J Su… - Journal of Hematology & …, 2015 - Springer
Background Neoadjuvant erlotinib and customized adjuvant therapy are appealing but
controversial. The purpose of this study was to evaluate the role of biomarker-guided …

[HTML][HTML] Gefitinib as neoadjuvant therapy for resectable stage II-IIIA non–small cell lung cancer: A phase II study

Y Zhang, F Fu, H Hu, S Wang, Y Li, H Hu… - The Journal of Thoracic …, 2021 - Elsevier
Introduction Currently, limited data on tyrosine kinase inhibitors as neoadjuvant therapy
exist. This prospective study aimed to investigate the efficacy and safety of preoperative …

Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - The Lancet …, 2018 - thelancet.com
Background Adjuvant chemotherapy after radical resection of stage IIIA non-small-cell lung
cancer (NSCLC) has quite poor outcomes. We aimed to investigate whether adjuvant …

Tumor response and toxicity of neoadjuvant erlotinib in patients with early-stage non–small-cell lung cancer

EE Schaake, I Kappers, HE Codrington… - Journal of clinical …, 2012 - ascopubs.org
Purpose The development of targeted therapy has introduced new options to improve
treatment outcome in selected patients. The objective of this prospective study was to …

Pemetrexed-carboplatin adjuvant chemotherapy with or without gefitinib in resected stage IIIA-N2 non-small cell lung cancer harbouring EGFR mutations: a …

N Li, W Ou, X Ye, HB Sun, L Zhang, Q Fang… - Annals of surgical …, 2014 - Springer
Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) show
great efficacy in patients with advanced non-small cell lung cancer (NSCLC) with EGFR …