Epigenetic modifications such as DNA methylation have large effects on gene expression
and genome maintenance. Helicobacter pylori, a human gastric pathogen, has a large …

The methylome is defined as a map of DNA methylation patterns at single-base resolution.
DNA methylation in bacteria was first discovered as a function of restriction–modification …

The bacterial pathogen Helicobacter pylori, the leading cause of gastric cancer, is
genetically highly diverse and harbours a large and variable portfolio of restriction …

Background The genome of the human gastric pathogen Helicobacter pylori encodes a
large number of DNA methyltransferases (MTases), some of which are shared among many …

The genome of Helicobacter pylori is remarkable for its large number of restriction-
modification (RM) systems, and strain-specific diversity in RM systems has been suggested …

Helicobacter pylori encodes a large number of restriction–modification (R–M) systems
despite its small genome. R–M systems have been described as 'primitive immune systems' …

The genome sequences of three Helicobacter pylori strains revealed an abundant number
of putative restriction and modification (RM) systems within a small genome (1.60 to 1.67 …

Decoding of closely related genomes is now revealing the process of population evolution.
In bacteria, population divergence appears associated with a unique set of sequence …

DNA methylation is one of the best studied epigenetic modifications observed in prokaryotes
as well as eukaryotes. It affects nearby gene expression. Most DNA methylation reactions in …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …