Cocrystallization and coamorphization are similar yet independent approaches toward
modifying various pharmaceutically relevant properties of modern drug compounds, in …

Improving the stability, bioavailability, and processability of active pharmaceutical
ingredients (APIs) has been the key research goal in the field of pharmaceutical …

In this work, the solvent-mediated phase transformation of the metastable form (Form II) to
the stable form (Form I) of ethenzamide–saccharin cocrystal in isopropanol was …

Non-isothermal differential scanning calorimetry was used to study the influences of particle
size and mechanically induced defects on the recrystallization kinetics of amorphous …

Biopharmaceutics Classification System (BCS) Class II and IV drugs suffer from poor
aqueous solubility and hence low bioavailability. Most of these drugs are hydrophobic and …

Pharmaceutical cocrystallization affords an opportunity to modify the physicochemical
properties of a solid-state drug without covalent modification of its molecular structure. This …

Cocrystallization is commonly used for its ability to improve the physical properties of APIs,
such as solubility, bioavailability, compressibility, etc. The pharmaceutical industry is …

Cocrystal formation may affect manufacturability (flow, compaction and processability) as
well as solubility/dissolution, hygroscopicity and stability properties of drugs. Therefore …

Recrystallization kinetics of amorphous Enzalutamide (two batches prepared by hot-melt
extrusion and thermal evaporation of the solvent) was studied by differential scanning …

Crystal engineering and co-crystallization have evolved in recent years and gained a
special interest not only in academia but also in the pharmaceutical field as it has been …