Lymph vessels: the forgotten second circulation in health and disease

LA Adamczyk, K Gordon, I Kholová, LB Meijer-Jorna… - Virchows Archiv, 2016 - Springer
The lymphatic circulation is still a somewhat forgotten part of the circulatory system. Despite
this, novel insights in lymph angiogenesis in health and disease, application of immune …

Markers for microscopic imaging of lymphangiogenesis and angiogenesis

P Baluk, DM McDonald - Annals of the New York Academy of …, 2008 - Wiley Online Library
Imaging of lymphangiogenesis and angiogenesis requires robust and unambiguous
markers of lymphatic and blood vessels. Although much progress has been made in recent …

Lymphangiogenesis in tumors: what do we know?

JS Reis‐Filho, FC Schmitt - Microscopy research and technique, 2003 - Wiley Online Library
Lymphangiogenesis, the growth of new lymphatic vessels, has long been regarded as a
putative efficient pathway to neoplastic metastization. However, until recently consistent data …

Lymphangiogenesis and expression of specific molecules as lymphatic endothelial cell markers

S Kato, H Shimoda, RC Ji… - Anatomical Science …, 2006 - Wiley Online Library
In recent years, several functional molecules specifically expressed and localized in
lymphatic endothelial cells, such as 5′‐nucleotidase, lymphatic vessel endothelial receptor …

[HTML][HTML] Key molecules in lymphatic development, function, and identification

SK Jha, K Rauniyar, M Jeltsch - Annals of Anatomy-Anatomischer Anzeiger, 2018 - Elsevier
While both blood and lymphatic vessels transport fluids and thus share many similarities,
they also show functional and structural differences, which can be used to differentiate them …

Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics

RC Ji - Cancer and Metastasis Reviews, 2006 - Springer
Lymphatic metastasis of tumor cells represents a series of extremely complex and
sequential processes that include dissemination and invasion into surrounding stromal …

Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation

P Saharinen, T Tammela, MJ Karkkainen, K Alitalo - Trends in immunology, 2004 - cell.com
The lymphatic vascular system is important for immune surveillance, tissue fluid
homeostasis and fat absorption, and is involved in many pathological processes, including …

Lymphatic endothelial regulation, lymphoedema, and lymph node metastasis

MJ Karkkainen, K Alitalo - Seminars in cell & developmental biology, 2002 - Elsevier
Vascular endothelial growth factor receptor-3 (VEGFR-3) mediates lymphatic endothelial
cell (LEC) growth, migration, and survival by binding VEGF-C and VEGF-D. Recent studies …

Lymphangiogenesis and its role in cancer

MAA Al-Rawi, RE Mansel, WG Jiang - Histology and histopathology, 2005 - digitum.um.es
In many tumour types, lymphatic vasculature serves as a major route for tumour metastasis.
The dissemination of malignant cells to the regional lymph nodes is an early step in the …

The lymphatic vasculature revisited

D Kerjaschki - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Lymphatic vessels constitute a ubiquitous countercurrent system to the blood vasculature
that returns interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream …