Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

Macrophages are plastic and functionally diverse, present in all tissues, and play a key role
in organisms from development, homeostasis and repair, to immune responses to …

The fact that various immune cells, including macrophages, can be found in tumor tissues
has long been known. With the introduction of concept that macrophages differentiate into a …

The fact that various immune cells, including macrophages, can be found in tumor tissues
has long been known. With the introduction of concept that macrophages differentiate into a …

High macrophage infiltration into tumours often correlates with poor prognoses; in colorectal,
stomach and skin cancers, however, the opposite is observed but the mechanisms behind …

Tumor-associated macrophages (TAMs) represent the most abundant innate immune cells
in tumors. TAMs, exhibiting anti-inflammatory phenotype, are key players in cancer …

Tumor microenvironment consists of malignant and non-malignant cells. The interaction of
these dynamic and different cells is responsible for tumor progression at different levels. The …

Tumor-associated macrophages (TAMs) are major component of leukocytic infiltrate of
tumors and play important roles in progression and regression of tumors. Tumor …

Macrophages, an important class of innate immune cells that maintain body homeostasis
and ward off foreign pathogens, exhibit a high degree of plasticity and play a supportive role …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …