Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE

B Petrelli, J Weinberg, GG Hicks - Biochemistry and Cell …, 2018 - cdnsciencepub.com
The potential impact of prenatal alcohol exposure (PAE) varies considerably among
exposed individuals, with some displaying serious alcohol-related effects and many others …

What happens when children with fetal alcohol spectrum disorders become adults?

EM Moore, EP Riley - Current developmental disorders reports, 2015 - Springer
The range of structural abnormalities and functional deficits caused by prenatal alcohol
exposure (PAE) are referred to as fetal alcohol spectrum disorders (FASDs). The disabilities …

The impact of paternal alcohol consumption on offspring brain and behavioral development

KE Conner, RT Bottom… - Alcoholism: Clinical and …, 2020 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) describe the wide array of long‐
lasting developmental abnormalities in offspring due to prenatal alcohol (ethanol [EtOH]) …

The impact of prenatal alcohol exposure on social, cognitive and affective behavioral domains: Insights from rodent models

K Marquardt, JL Brigman - Alcohol, 2016 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) are characterized by deficits in working
memory, response inhibition, and behavioral flexibility. However, the combination and …

The impact of prenatal ethanol exposure on neuroanatomical and behavioral development in mice

CW Abbott, OO Kozanian, J Kanaan… - Alcoholism: Clinical …, 2016 - Wiley Online Library
Background In utero alcohol, or ethanol (EtOH), exposure produces developmental
abnormalities in the brain of the fetus, which can result in lifelong behavioral abnormalities …

Murine models for the study of fetal alcohol spectrum disorders: An overview

L Almeida, V Andreu-Fernández… - Frontiers in …, 2020 - frontiersin.org
Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and
neurological impairments collectively known as fetal alcohol spectrum disorder. The …

Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders

ML Kleiber, EJ Diehl, BI Laufer, K Mantha… - Frontiers in …, 2014 - frontiersin.org
There is abundant evidence that prenatal alcohol exposure leads to a range of behavioral
and cognitive impairments, categorized under the term fetal alcohol spectrum disorders …

Genetic influences on fetal alcohol spectrum disorder

D Sambo, D Goldman - Genes, 2023 - mdpi.com
Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of
prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay …

Overview of the genetic basis and epigenetic mechanisms that contribute to FASD pathobiology

V RB Liyanage, K Curtis, RM Zachariah… - Current topics in …, 2017 - ingentaconnect.com
Prenatal alcohol (ethanol) exposure (PAE) is the underlying cause for a variety of birth
defects and neurodevelopmental deficits referred to as “Fetal Alcohol Spectrum Disorders …

Mental health outcomes associated with prenatal alcohol exposure: genetic and environmental factors

MJ O'Connor - Current Developmental Disorders Reports, 2014 - Springer
Overwhelming evidence on the impact of maternal alcohol consumption during pregnancy
has prompted increased attention to the link between prenatal alcohol exposure (PAE) and …