[图书][B] Desensitization and resensitization of the cloned capsaicin receptor (VR1): Regulation of the receptor sensitivity by phosphorylation
H Wang - 2001 - search.proquest.com
Capsaicin is the main pungent ingredient of hot chili peppers and selectively activates
nociceptive sensory neurons to exert the burning pain sensation. However, a prolonged …
nociceptive sensory neurons to exert the burning pain sensation. However, a prolonged …
Capsaicin receptor and its homologue in nociception
M Tominaga - Pain Reviews, 2000 - search.proquest.com
Capsaicin, the main ingredient in'hot'chilli peppers, elicits burning pain by activating specific
(vanilloid) receptors on sensory nerve endings. The cloned capsaicin receptor (VR1) is a …
(vanilloid) receptors on sensory nerve endings. The cloned capsaicin receptor (VR1) is a …
Capsaicin, protons and heat: new excitement about nociceptors
M Kress, HU Zeilhofer - Trends in pharmacological sciences, 1999 - cell.com
The past few years have witnessed a remarkable progress in understanding the
neurobiology of pain. Important advances have been made particularly in the field of …
neurobiology of pain. Important advances have been made particularly in the field of …
Acid potentiation of the capsaicin receptor determined by a key extracellular site
SE Jordt - Journal of Neurochemistry, 2003 - Wiley Online Library
The capsaicin receptor, VR1, is a sensory neuron‐specific ion channel that serves as a
detector of pain‐producing chemical and physical stimuli. The response of VR1 to capsaicin …
detector of pain‐producing chemical and physical stimuli. The response of VR1 to capsaicin …
Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia
RJA Helliwell, LM McLatchie, M Clarke, J Winter… - Neuroscience …, 1998 - Elsevier
A vanilloid receptor (VR1) has recently been cloned and shown to be a target for capsaicin,
the excitotoxic component of capsicum peppers (Caterina, MJ, Schumacher, MA, Tominaga …
the excitotoxic component of capsicum peppers (Caterina, MJ, Schumacher, MA, Tominaga …
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cε and identification of two target serine residues
M Numazaki, T Tominaga, H Toyooka… - Journal of Biological …, 2002 - ASBMB
The capsaicin receptor, VR1, is a sensory neuron-specific ion channel that serves as a
polymodal detector of pain-producing chemical and physical stimuli. It has been reported …
polymodal detector of pain-producing chemical and physical stimuli. It has been reported …
Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal domain suggests functional divergence among capsaicin receptor …
MA Schumacher, I Moff, SP Sudanagunta… - Journal of Biological …, 2000 - ASBMB
Recently a cDNA clone, vanilloid receptor subtype-1 (VR1), was isolated and found to
encode an ion channel that is activated by both capsaicin, the pain producing compound in …
encode an ion channel that is activated by both capsaicin, the pain producing compound in …
Vanilloid receptor-mediated hyperalgesia and desensitization
Z Sándor, A Szallasi - Turning up the Heat on Pain: TRPV1 Receptors in …, 2005 - Springer
“There are compounds that can selectively desensitize sensory nerve endings to noxious
chemical stimuli without causing local anesthesia…. Capsaicin is the paradigm of such …
chemical stimuli without causing local anesthesia…. Capsaicin is the paradigm of such …
[PDF][PDF] The cloned capsaicin receptor integrates multiple pain-producing stimuli
M Tominaga, MJ Caterina, AB Malmberg, TA Rosen… - Neuron, 1998 - cell.com
Capsaicin, the main pungent ingredient in" hot" chili peppers, elicits burning pain by
activating specific (vanilloid) receptors on sensory nerve endings. The cloned vanilloid …
activating specific (vanilloid) receptors on sensory nerve endings. The cloned vanilloid …
[HTML][HTML] Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain
Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …
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- capsaicin receptor desensitization and resensitization
- capsaicin receptor direct phosphorylation
- capsaicin receptor functional divergence
- capsaicin receptor acid potentiation
- capsaicin receptor splice variant
- capsaicin receptor molecular cloning
- capsaicin receptor protein kinase
- receptor sensitivity desensitization and resensitization