Synthesis of novel tetrazole derivatives and evaluation of their antifungal activity
E Łukowska-Chojnacka, J Mierzejewska… - Bioorganic & Medicinal …, 2016 - Elsevier
With the appearance of the antifungal resistance, novel antifungal agents need to be
identified. In this context new 2, 5-disubstituted tetrazole derivatives containing …
identified. In this context new 2, 5-disubstituted tetrazole derivatives containing …
Synthesis of tetrazole derivatives bearing pyrrolidine scaffold and evaluation of their antifungal activity against Candida albicans
E Łukowska-Chojnacka, A Kowalkowska… - European journal of …, 2019 - Elsevier
The increase of opportunistic fungal infections raises the need for design and synthesis of
new antifungal agents. Taking into account that tetrazole derivatives exhibit antifungal …
new antifungal agents. Taking into account that tetrazole derivatives exhibit antifungal …
Design, synthesis, and evaluation of novel tetrazoles featuring isoxazole moiety as highly selective antifungal agents
T Ni, X Chi, F Xie, L Li, H Wu, Y Hao, X Wang… - European Journal of …, 2023 - Elsevier
In an effort to develop novel azole antifungals with potent activity and high selectivity, a
series of (2R, 3R)-3-((3-substitutied-phenyl-isoxazol-5-yl) methoxy)-2-(2, 4-difluorophenyl)-1 …
series of (2R, 3R)-3-((3-substitutied-phenyl-isoxazol-5-yl) methoxy)-2-(2, 4-difluorophenyl)-1 …
New 1, 5 and 2, 5-disubstituted tetrazoles-dependent activity towards surface barrier of Candida albicans
M Staniszewska, M Gizińska, E Mikulak… - European Journal of …, 2018 - Elsevier
A series of novel tetrazole derivatives was synthetized using N-alkylation or Michael-type
addition reactions, and screened for their fungistatic potential against Candida albicans (the …
addition reactions, and screened for their fungistatic potential against Candida albicans (the …
Synthesis of selected 5-thio-substituted tetrazole derivatives and evaluation of their antibacterial and antifungal activities
V Dhayanithi, SS Shafi, K Kumaran… - Journal of the Serbian …, 2011 - doiserbia.nb.rs
Several 5-thio-substituted tetrazole derivatives were efficiently synthesized by a three-step
process. The substituted tetrazol-5-thiol, namely, 1-benzyl-1H-tetrazol-5-thiol (2) was …
process. The substituted tetrazol-5-thiol, namely, 1-benzyl-1H-tetrazol-5-thiol (2) was …
Synthesis of novel substituted tetrazoles having antifungal activity
RS Upadhayaya, S Jain, N Sinha, N Kishore… - European journal of …, 2004 - Elsevier
In an effort to find potent antifungal agents, a variety of triazole derivatives with a 5-
substituted tetrazole structure 6, 7, 12 and 14 were prepared and evaluated for antifungal …
substituted tetrazole structure 6, 7, 12 and 14 were prepared and evaluated for antifungal …
Discovery of Novel Tetrazoles Featuring a Pyrazole Moiety as Potent and Highly Selective Antifungal Agents
X Chi, H Zhang, H Wu, X Li, L Li, Y Jiang, T Ni - ACS omega, 2023 - ACS Publications
In pursuit of developing novel azole antifungals with potent activity and high selectivity, a
series of (2 R, 3 S)-3-(substituted-1 H-pyrazol-3-yl)-2-(2, 4-difluorophenyl)-1-(1 H-tetrazol-1 …
series of (2 R, 3 S)-3-(substituted-1 H-pyrazol-3-yl)-2-(2, 4-difluorophenyl)-1-(1 H-tetrazol-1 …
Design, synthesis, antimicrobial and antifungal activities of new 1, 2, 4-triazole derivatives containing 1H-tetrazole moiety
Y Frolova, A Kaplaushenko… - Journal of Faculty of …, 2020 - dergipark.org.tr
Objective: Antimicrobials and antifungals are the most acquired drugs in the world. Today, it
becomes necessary to create new drugs with antimicrobial and antifungal effect. The …
becomes necessary to create new drugs with antimicrobial and antifungal effect. The …
Amide analogs of antifungal dioxane–triazole derivatives: Synthesis and in vitro activities
T Uchida, Y Kagoshima, T Konosu - Bioorganic & medicinal chemistry …, 2009 - Elsevier
A new series of triazole compounds possessing an amide-part were efficiently synthesized
and their in vitro antifungal activities were investigated. The amide analogs showed …
and their in vitro antifungal activities were investigated. The amide analogs showed …
Synthesis and antifungal activity of 1, 2, 4-triazole derivatives containing cyclopropane moiety
CX Tan, YX Shi, JQ Weng, XH Liu… - Letters in Drug …, 2012 - ingentaconnect.com
A new series of 1, 2, 4-triazoles containing cyclopropane moiety were synthesized and
characterized by 1H NMR and elemental analyses. The biological activities results showed …
characterized by 1H NMR and elemental analyses. The biological activities results showed …