Pyroptosis, and its role in central nervous system disease
Pyroptosis is an inflammatory form of cell death executed by transmembrane pore-forming
proteins known as gasdermins and can be activated in an inflammasome-dependent or …
proteins known as gasdermins and can be activated in an inflammasome-dependent or …
Fiery cell death: pyroptosis in the central nervous system
Pyroptosis ('fiery death') is an inflammatory type of regulated cell death (RCD), which occurs
downstream of inflammasome activation. Pyroptosis is mediated directly by the recently …
downstream of inflammasome activation. Pyroptosis is mediated directly by the recently …
Role of pyroptosis in the pathogenesis of various neurological diseases
A Oladapo, T Jackson, J Menolascino… - Brain, Behavior, and …, 2024 - Elsevier
Pyroptosis, an inflammatory programmed cell death process, has recently garnered
significant attention due to its pivotal role in various neurological diseases. This review …
significant attention due to its pivotal role in various neurological diseases. This review …
Research progress of pyroptosis in alzheimer's disease
W Xue, D Cui, Y Qiu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is a disease characterized by insidious and progressive
neurodegeneration, with clinical syndromes of memory and visuospatial skills damage. The …
neurodegeneration, with clinical syndromes of memory and visuospatial skills damage. The …
Mechanism of pyroptosis in neurodegenerative diseases and its therapeutic potential by traditional Chinese medicine
Y Liao, X Wang, L Huang, H Qian, W Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
Neurodegenerative diseases (NDs) are disorders characterized by degenerative
degeneration of neurons and loss of their function. NDs have a complicated …
degeneration of neurons and loss of their function. NDs have a complicated …
The role of pyroptosis in inflammatory diseases
R Chai, Y Li, L Shui, L Ni, A Zhang - Frontiers in Cell and …, 2023 - frontiersin.org
Programmed cell death has crucial roles in the physiological maturation of an organism, the
maintenance of metabolism, and disease progression. Pyroptosis, a form of programmed …
maintenance of metabolism, and disease progression. Pyroptosis, a form of programmed …
Targeting pyroptosis to regulate ischemic stroke injury: molecular mechanisms and preclinical evidences
A Ye, W Li, L Zhou, L Ao, W Fang, Y Li - Brain Research Bulletin, 2020 - Elsevier
Stroke is one of the leading causes of death worldwide with limited therapies. After ischemic
stroke occurs, a robust sterile inflammatory response happens and lasts for days and …
stroke occurs, a robust sterile inflammatory response happens and lasts for days and …
Pyroptosis: a promising therapeutic target for noninfectious diseases
T Li, G Zheng, B Li, L Tang - Cell proliferation, 2021 - Wiley Online Library
Pyroptosis, which is characterized by gasdermin family protein‐mediated pore formation,
cellular lysis and the release of pro‐inflammatory cytokines, is a form of programmed cell …
cellular lysis and the release of pro‐inflammatory cytokines, is a form of programmed cell …
Role of pyroptosis in inflammation and cancer
X Wei, F Xie, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
Pyroptosis in spinal cord injury
J Yin, G Gong, W Wan, X Liu - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Spinal cord injury (SCI) often brings devastating consequences to patients and their families.
Pathophysiologically, the primary insult causes irreversible damage to neurons and glial …
Pathophysiologically, the primary insult causes irreversible damage to neurons and glial …