Hepatic encephalopathy (HE) is a common neurological manifestation of liver cirrhosis and
is characterized by an increase of ammonia in the brain accompanied by a disrupted …

The pathogenesis of hepatic encephalopathy (HE) is not fully understood yet.
Hyperammonemia due to liver failure and subsequent disturbance of cerebral osmolytic …

Purpose To conduct the first investigation on thalamic metabolic alterations in minimal
hepatic encephalopathy (MHE) and elucidate their association with intrinsic neural activity …

Minimal hepatic encephalopathy (MHE) is frequently diagnosed in patients with liver
cirrhosis who do not show overt clinical cirrhosis-associated neurological deficits. This …

Background: Hepatic encephalopathy (HE) is considered to be mainly due to increased
ammonia metabolism of the brain. If this hypothesis is true, cerebral glucose utilisation …

Background: Hepatic encephalopathy is considered to be mainly caused by increased
ammonia metabolism of the brain. If this hypothesis is true, cerebral glucose utilisation …

Introduction Type C hepatic encephalopathy (HE) is a decompensating event of chronic liver
disease leading to severe motor and cognitive impairment. The progression of type C HE is …

Aim To examine whether the brain exhibits metabolic disorder prior to overt hepatic
encephalopathy in patients with liver cirrhosis (LC), the intracerebral glutamine and myo …

Objective To evaluate regional cerebral metabolic changes in minimal hepatic
encephalopathy (MHE) patients using magnetic resonance spectroscopy (MRS) in 3T …

Results The brain metabolite Glx increased with a significant correlation to HE grade (p=
0.001). Other brain metabolites, such as Cho and mI, decreased significantly (p= 0.001) …