Protein kinase CK2, a protein serine/threonine kinase, plays a global role in activities related
to cell growth, cell death, and cell survival. CK2 has a large number of potential substrates …

The association of protein kinase CK2 (formerly casein kinase II or 2) with cell growth and
proliferation in cells was apparent at early stages of its investigation. A cancer-specific role …

Elevated levels of protein kinase CK2 (formerly casein kinase 2 or II) have long been
associated with increased cell growth and proliferation both in normal and cancer cells. The …

CK2 is a highly conserved protein serine/threonine kinase that is ubiquitously distributed in
eukaryotes, constitutively active and has been implicated in multiple cellular functions, as …

Recent studies have generated sufficient information to warrant a consideration of protein
kinase CK2 as a potential target for cancer therapy. CK2 is a ubiquitous and highly …

Protein kinase CK2 is a constitutively active protein serine/threonine kinase that is
ubiquitously expressed and essential for the survival of eukaryotic cells. On the basis of its …

CK2 is probably the most pleiotropic Ser/Thr protein kinase with hundreds of endogenous
substrates already known, which are implicated in a variety of cellular functions. At variance …

CK2 genes are overexpressed in many human cancers, and most often overexpression is
associated with worse prognosis. Site-specific expression in mice leads to cancer …

Protein kinase CK2 (formerly referred to as casein kinase II) is an evolutionary conserved,
ubiquitous protein kinase. There are two paralog catalytic subunits, ie alpha (A1) and …

Protein kinase CK2 is a protein serine/threonine kinase that exhibits elevated expression in
a number of cancers and displays oncogenic activity in mice. The regulatory CK2β subunit …