Reactivation of Latent Human Cytomegalovirus in CD14+ Monocytes Is Differentiation Dependent

C Söderberg-Nauclér, DN Streblow, KN Fish… - Journal of …, 2001 - Am Soc Microbiol
We have previously demonstrated reactivation of latent human cytomegalovirus (HCMV) in
myeloid lineage cells obtained from healthy donors. Virus was obtained from allogenically …

Interferon-gamma and tumor necrosis factor-alpha specifically induce formation of cytomegalovirus-permissive monocyte-derived macrophages that are refractory to …

C Söderberg-Nauclér, KN Fish… - The Journal of clinical …, 1997 - Am Soc Clin Investig
Monocytes/macrophages are key cells in the pathogenesis of human cytomegalovirus
(HCMV). Although HCMV infection in monocytes is restricted to early events of gene …

Human cytomegalovirus productively infects primary differentiated macrophages

CE Ibanez, R Schrier, P Ghazal, C Wiley… - Journal of …, 1991 - Am Soc Microbiol
Monocytes are one of the predominant cell types in the peripheral blood that are infected by
human cytomegalovirus (HCMV). Although virus can be detected in these cells in vivo …

Growth kinetics of human cytomegalovirus are altered in monocyte-derived macrophages

KN Fish, AS Depto, AV Moses, W Britt… - Journal of virology, 1995 - Am Soc Microbiol
Stimulation of monocytes/macrophages with activated nonadherent cells allows productive
nonlytic growth of human cytomegalovirus (HCMV), but the viral replication cycle is delayed …

Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors

M Mendelson, S Monard… - Journal of General …, 1996 - microbiologyresearch.org
The cellular sites and mechanisms of human cytomegalovirus (HCMV) latency are still
poorly defined. Although evidence suggests that peripheral blood monocytes are one site of …

Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers

J Taylor-Wiedeman, P Sissons, J Sinclair - Journal of virology, 1994 - Am Soc Microbiol
Monocytes are one site of carriage of the human cytomegalovirus (HCMV) genome in
healthy human carriers. However, as there are conflicting data detailing the level of HCMV …

Human cytomegalovirus infection of human hematopoietic progenitor cells

JP Maciejewski, SC St Jeor - Leukemia & lymphoma, 1999 - Taylor & Francis
For a number of years it has been well established that human Cytomegalovirus (HCMV)
can be transmitted by the cellular components of blood. HCMV is also associated with a …

Human cytomegalovirus reactivation in bone-marrow-derived granulocyte/monocyte progenitor cells and mature monocytes

S Prösch, WD Döcke, P Reinke, HD Volk, DH Krüger - Intervirology, 2000 - karger.com
Monocyte/granulocyte progenitor cells of the bone marrow are a major site of human
cytomegalovirus (HCMV) latency. The mechanisms of establishment and maintenance of …

Human cytomegalovirus infection of the monocyte/macrophage lineage in bone marrow

EJ Minton, C Tysoe, JH Sinclair, JG Sissons - Journal of virology, 1994 - Am Soc Microbiol
Peripheral blood monocytes (PBM) are one site of persistence of human cytomegalovirus
(HCMV) in healthy carriers. However, because PBM circulate only briefly before entering the …

Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus

S Riegler, H Hebart, H Einsele… - Journal of General …, 2000 - microbiologyresearch.org
The susceptibility of monocyte-derived immature dendritic cells (DC) to infection by various
strains of human cytomegalovirus (HCMV) was analysed. Immature DC were generated by …