Since its discovery, Helicobacter pylori has been identified as the causative agent of various
gastric diseases. H. pylori produces myriads of disease-associated virulence factors. These …

Helicobacter pylori is a pathogenic bacterium that colonizes more than 50% of the world's
population, which leads to a tremendous medical burden. H. pylori infection is associated …

Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the
major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer …

The intensive study of urease, motility, adhesins and stress response proteins, long-known
pathogenic factors of Helicobacter pylori, has continued. The increased virulence associated …

Numerous Helicobacter pylori virulence factors, including various enzymes (urease,
catalase, lipase, phospholipase and proteases), vacuolating cytotoxin (a product of …

Helicobacter pylori is a very successful Gram-negative pathogen colonizing the stomach of
humans worldwide. Infections with this bacterium can generate pathologies ranging from …

The study of the virulence factors that enable Helicobacter pylori to colonize its unique
ecological niche has always been one of the most dynamic areas of H. pylori research. This …

A number of putative virulence factors for Helicobacter pylori have been identified including
cagA, vacA and iceA. The criteria for a true virulence factor includes meeting the tests of …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

To date a number of virulence factors have been identified and characterised from the
gastric pathogen Helicobacter pylori. The vacuolating toxin (VacA) is a major determinant of …