Polycystic ovary syndrome is a multifactorial condition associated with reproductive and
endocrine organs and might cause infertility and metabolic abnormalities in childbearing …

OBJECTIVE: To analyze promoter regions of CYP11A1 and CYP17 for putative variations in
a defined group of women with polycystic ovary syndrome (PCOS) and to study their …

Purpose Polycystic ovary syndrome (PCOS) is a complex multifactorial endocrine disorder
affecting approximately 5–10% of women of reproductive age. Affected women have …

Background Polycystic ovarian syndrome (PCOS) is considered the most common
multifactorial endocrinopathy. Genetic factors play an essential role in the pathogenesis of …

Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early
reproductive age in women, whose pathophysiology perplexes many researchers till today …

The cholesterol side chain cleavage enzyme (CYP11A1) gene plays an important part in the
synthesis of sex hormones and has been reported to be involved in the pathogenesis of …

The T→ C polymorphism of CYP17 gene has been inconsistently associated with polycystic
ovary syndrome (PCOS) risk. We examined the association by performing a meta-analysis …

CYP11A, the gene encoding P450scc, a key enzyme in steroid biosynthesis, is a strong
biological candidate for polycystic ovary syndrome (PCOS) susceptibility. Four of the five …

Background Polycystic ovary syndrome (PCOS) is a condition with central feature of
hyperandrogensism that affects 5-12% of women worldwide. P450sec the cholesterol side …

Abstract Cytochrome P450-C17 enzyme (CYP17) is an important component of the
androgen synthesis pathway, a pathway that is dysfunctional in polycystic ovary syndrome …