Alzheimer's disease (AD) is a progressive neurogenerative disorder manifested by gradual
memory loss and cognitive decline due to profound damage of cholinergic neurons. The …

Alzheimer's disease (AD) is a neurodegenerative disorder and leading cause of dementia,
which begins with impaired memory. The neuropathological hallmarks of AD include …

Chemokines are a family of cytokines, first described to play a role in the immune system.
However, neurons and glial cells also express chemokines and their receptors. In the central …

In recent years, increasing attention has been focused on chemokines as inflammatory
mediators in the CNS. The limited number of studies that have investigated chemokine and …

Objective: The most common multifactorial neurodegenerative disorder occurring in old age
is Alzheimer's disease. The neuropathological hallmarks of that disorder are amyloid …

Chemokines and their receptors have been shown to affect amyloid-β (Aβ) and tau
pathologies in mouse models of Alzheimer's disease (AD) by regulating microglia and …

Chemokines secreted by astrocytes play multiple roles in the pathology of Alzheimer's
disease, a chronic inflammation disorder of central nervous system. The level of chemokines …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and the
fourth leading cause of death in the United States. Its pathological changes include amyloid …

Inflammation is an innate mechanism that defends organisms against harmful stimuli.
Inflammation leads to the production and secretion of proinflammatory mediators that …

Alzheimer's disease (AD) is the commonest form of adult onset dementia and is
characterised neuropathologically by the accumulation of plaques containing β-amyloid (Aβ) …