Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Accumulating evidence indicates that obesity is closely associated with an increased risk of
metabolic diseases such as insulin resistance, type 2 diabetes, dyslipidemia and …

Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

Immoderate energy intake, a sedentary lifestyle, and aging have contributed to the
increased prevalence of obesity, sarcopenia, metabolic syndrome, type 2 diabetes, and …

Obesity is a syndemia that promotes high expenditures for public health, and is defined by
the excess of adipose tissue that is classified according to its function and anatomical …

It is well established that adipose tissue, apart from its energy storage function, acts as an
endocrine organ that produces and secretes a number of bioactive substances, including …

Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …