In silico and In vivo Studies of Calotropis procera leaf and root extracts on Mitochondrial-Related parameters in Wistar Rats
AD Adisa, PF Olabinri, AT Oyedeji… - IPS Journal of …, 2023 - drugdiscoveryupdate.com
Abstract Drugs targeting Mitochondrial Membrane Permeability Transition (MMPT) pore
opening are of great interest for conditions arising from apoptosis dysregulation. This study …
opening are of great interest for conditions arising from apoptosis dysregulation. This study …
Modulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential using in silico approach
Myricetin has been demonstrated to have multiple biological functions with promising
research and development prospects. This study investigated the effect of myricetin on liver …
research and development prospects. This study investigated the effect of myricetin on liver …
In Silico Evaluation of Kaempferol and Its Semisynthetic Derivative As mTORC1 Inhibitor Against Hepatocellular Carcinoma Using Molecular Docking and ADMET …
P Prasad, KN PK, DL R Nath - Silico Evaluation of Kaempferol …, 2020 - papers.ssrn.com
Hepatocellular carcinoma (HCCs) are inherently chemotherapy-resistant tumors and the
activation of PI3K/Akt/mTOR pathway confers resistance to chemotherapy in 30-50% of …
activation of PI3K/Akt/mTOR pathway confers resistance to chemotherapy in 30-50% of …
In silico evaluation of the binding mechanism of Rhododendron arboreum bioactives against catechol-o-methyltransferase in Parkinson's disease
D Paul, MR D'Souza - Medicinal Plants-International Journal of …, 2023 - indianjournals.com
Parkinson's disease (PD), the second most prevalent neurodegenerative disease affecting
individuals at 50–60 years of age, still does not have any cure. Even the golden therapy for …
individuals at 50–60 years of age, still does not have any cure. Even the golden therapy for …
Isolation, Characterization, Antimicrobial and Theoretical Investigation of Some Bioactive Compounds Obtained from the Bulbs of Calotropisprocera
ME Khan, CE Elum, AO Ijeomah… - Journal of the …, 2023 - journal.nsps.org.ng
This study characterizes the bioactive molecules from the bulb of Calotropisprocera and
investigates the antimicrobial activities of the crude extracts. Theoretical studies on the two …
investigates the antimicrobial activities of the crude extracts. Theoretical studies on the two …
[PDF][PDF] In Silico Molecular Docking Analysis of Flavone and Phytol from Vilvam (Aegle marmelos) against Human Hepatocellular Carcinoma (HepG-2) Mitochondrial …
S Anbazhagan, S Kanakarajan… - Int. J. Exp. Res …, 2023 - pdfs.semanticscholar.org
The vilvam fruit is an important source of phyto compounds, that are a good natural resource
for curing several health illnesses. Annually, around 906,000 new cases and 830,000 …
for curing several health illnesses. Annually, around 906,000 new cases and 830,000 …
Phytochemical Profiling, Antioxidant, Anti-Inflammatory, Thrombolytic, Hemolytic Activity In Vitro and In Silico Potential of Portulacaria afra
S Tabassum, S Ahmad, K Rehman Khan, F Tabassum… - Molecules, 2022 - mdpi.com
The use of complementary herbal medicines has recently increased in an attempt to find
effective alternative therapies that reduce the adverse effects of chemical drugs. Portulacaria …
effective alternative therapies that reduce the adverse effects of chemical drugs. Portulacaria …
In Silico approach to predict the potential binding affinity of the active Ingredient of the Macrotyloma uniflorum seed against Orphan Nuclear Receptor
JS Peter, A Kappagantu… - Research Journal of …, 2021 - indianjournals.com
Objective: Liver damage is a severe metabolic disorder which is caused due to the
xenobiotic and oxidative stress. The liver plays an important role in maintaining the …
xenobiotic and oxidative stress. The liver plays an important role in maintaining the …
[PDF][PDF] ADMET prediction and molecular docking simulation of phytoconstituents in Boesenbergia rotunda rhizome with the effector caspases to understand their …
Acute kidney injury is a condition when kidney function decreased abruptly, characterized by
eg a decrease in the glomerular filtration rate. This condition is due to the activation of …
eg a decrease in the glomerular filtration rate. This condition is due to the activation of …
In vitro, in silico studies of newly isolated tetrahydro-4-(7-hydroxy-10-methoxy-6, 14-dimethyl-15-m-tolylpentadec-13-enyl) pyran-2-one and isobutyryl acetate …
Alstonia boonei is a medicinal plant use for the treatment of infections. In this study, two new
compounds were purified from Alstonia boonei stem bark using standard methods and their …
compounds were purified from Alstonia boonei stem bark using standard methods and their …