Statins with potential to control periodontitis: From biological mechanisms to clinical studies

RDP de Carvalho, RCV Casarin, PO de Lima… - Journal of Oral …, 2021 - Elsevier
Background Statins are widely used for the treatment of hyperlipidemia. However, these
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral …

Pleiotropic effects of statins on the treatment of chronic periodontitis–a systematic review

IMG Estanislau, IRC Terceiro… - British journal of …, 2015 - Wiley Online Library
Aim Statins are inhibitors of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase and are an
important group of hypolipidaemic drugs, widely used in the treatment of …

[HTML][HTML] Statin: A boon in periodontal therapy

S Purushotham, R Purushotham - SRM Journal of Research in …, 2015 - journals.lww.com
Periodontitis is an inflammatory process causing gradual destruction of the periodontal
tissues and alveolar bone loss. Various periodontal therapies have been introduced to lower …

Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta‐analysis of preclinical in vivo trials

K Bertl, I Steiner, N Pandis, K Buhlin… - Journal of …, 2018 - Wiley Online Library
The cholesterol‐lowering drugs, statins, possess anti‐inflammatory, antimicrobial and pro‐
osteogenic properties, and thus have been tested as an adjunct to periodontal treatment …

Contribution of statins towards periodontal treatment: a review

C Petit, F Batool, IM Bugueno, P Schwinté… - Mediators of …, 2019 - Wiley Online Library
The pleiotropic effects of statins have been evaluated to assess their potential benefit in the
treatment of various inflammatory and immune‐mediated diseases including periodontitis …

The effects of statins on dental and oral health: a review of preclinical and clinical studies

S Tahamtan, F Shirban, M Bagherniya… - Journal of translational …, 2020 - Springer
The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

[HTML][HTML] Statins: the paradigm shift in periodontal regeneration

P Kataria, J Kaur, E Parvez… - SRM Journal of Research …, 2014 - journals.lww.com
Statins, the lipid-lowering drugs, provide an important and effective approach for the
treatment of hyperlipidemia and arteriosclerosis. They function by reducing the blood …

Are statins worthy for treatment of periodontitis? A systematic review and meta-analysis

M Shah, P Muley, A Muley - Advances in Human Biology, 2017 - journals.lww.com
Background: Statins are drugs used for locking the synthesis of cholesterol as it inhibits 3-
hydroxy-3-methylglutaryl coenzyme A reductase. Besides action on cholesterol, statins also …

Statin use and tooth loss in chronic periodontitis patients

J Cunha‐Cruz, B Saver, G Maupome… - Journal of …, 2006 - Wiley Online Library
Background: Statins have anti‐inflammatory and bone stimulating properties that may
positively affect chronic periodontitis. Our objective in this study was to evaluate whether …

Statins and alveolar bone resorption: a narrative review of preclinical and clinical studies

E de Monès, S Schlaubitz, S Catros… - Oral surgery, oral medicine …, 2015 - Elsevier
Context Tooth extraction and periodontal disease are both common clinical situations
associated with alveolar bone loss. Objective To analyze the reported results of in vivo …