M‐CSF directs myeloid and NK cell differentiation to protect from CMV after hematopoietic cell transplantation

PK Kandalla, J Subburayalu, C Cocita… - EMBO Molecular …, 2023 - embopress.org
Therapies reconstituting autologous antiviral immunocompetence may represent an
important prophylaxis and treatment for immunosuppressed individuals. Following …

Prophylactic infusion of cytomegalovirus-specific cytotoxic T lymphocytes stimulated with Ad5f35pp65 gene-modified dendritic cells after allogeneic hemopoietic stem …

KP Micklethwaite, L Clancy, U Sandher… - Blood, The Journal …, 2008 - ashpublications.org
Cytomegalovirus (CMV) and its therapy continue to contribute to morbidity and mortality in
hemopoietic stem cell transplantation (HSCT). Many studies have demonstrated the …

Mutual interference between cytomegalovirus and reconstitution of protective immunity after hematopoietic cell transplantation

MJ Reddehase - Frontiers in immunology, 2016 - frontiersin.org
Hematopoietic cell transplantation (HCT) is a therapy option for aggressive forms of
hematopoietic malignancies that are resistant to standard antitumoral therapies …

Cytomegalovirus-specific T cell immunotherapy promotes restoration of durable functional antiviral immunity following allogeneic stem cell transplantation

KS Peggs, S Verfuerth, A Pizzey… - Clinical infectious …, 2009 - academic.oup.com
Background. The profound immunodeficiency associated with allogeneic hematopoietic
stem cell transplantation is permissive to uncontrolled replication of latent human …

Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model

MS Smith, DC Goldman, AS Bailey, DL Pfaffle… - Cell host & …, 2010 - cell.com
Human cytomegalovirus (HCMV) is a significant cause of morbidity and mortality in organ
transplant recipients. The use of granulocyte-colony stimulating factor (G-CSF)-mobilized …

Paracrine inhibition of GM-CSF signaling by human cytomegalovirus in monocytes differentiating to dendritic cells

J Carlier, H Martin, B Mariamé… - Blood, The Journal …, 2011 - ashpublications.org
A primary HCMV infection or virus reactivation may cause severe disease in hosts with a
deficient immune system. The virus can disturb both innate and adaptive immunity by …

Kinetics of interferon‐gamma producing cytomegalovirus (CMV)‐specific CD4+ and CD8+ T lymphocytes and the risk of subsequent CMV viremia after allogeneic …

AJ Eid, RA Brown, WJ Hogan, BD Lahr… - Transplant Infectious …, 2009 - Wiley Online Library
Background. Deficiencies in cytomegalovirus (CMV)‐specific T lymphocytes impair the
immunologic response against CMV reactivation after allogeneic hematopoietic stem cell …

The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the …

P Scheinberg, JJ Melenhorst… - Blood, The Journal …, 2009 - ashpublications.org
The successful reconstitution of adaptive immunity to human cytomegalovirus (CMV) in
hematopoietic stem cell transplantation (HSCT) recipients is central to the reduction of viral …

Immune control of cytomegalovirus reactivation in stem cell transplantation

MA Degli-Esposti, GR Hill - Blood, The Journal of the American …, 2022 - ashpublications.org
The reactivation of viruses from latency after allogeneic stem cell transplantation (SCT)
continues to represent a major clinical challenge requiring sophisticated monitoring …

[HTML][HTML] An assessment of the effect of human herpesvirus-6 replication on active cytomegalovirus infection after allogeneic stem cell transplantation

N Tormo, C Solano, R de la Cámara… - Biology of Blood and …, 2010 - Elsevier
Human herpesvirus-6 (HHV-6) may enhance cytomegalovirus (CMV) replication in
allogeneic stem cell transplant (allo-SCT) recipients either through direct or indirect …