Ketamine causes poor maternal care in rats with postpartum depression and leads to few behavioral and neurochemical alterations on male offspring

J Zaccarelli-Magalhães, GR Abreu… - Behavioural Brain …, 2024 - Elsevier
Ketamine is an anesthetic drug that also has antidepressant properties, with quick action.
Despite the great number of studies showing its effectiveness as a treatment for major …

Post-Partum Depression Lactating Rat Model for Evaluating Ketamine's Safety as a Pharmacotherapeutic Treatment: Roles in Cardiac and Urinary Function

AR Fukushima, PE Navas-Suárez… - Journal of …, 2022 - mdpi.com
Depression is one of the world's most common and mentally disabling illnesses. Post-
partum depression is a subtype of depression that affects one in seven women worldwide …

Effects of single-dose ketamine infusion on behavioral parameters and neuronal activation in the medial prefrontal cortex of juvenile rats exposed to prenatal stress

EP Çorumlu, OÖ Aydın, EG Aydın, E Ulupınar - Anatomy, 2015 - dergipark.org.tr
Objectives: Subanesthetic dose of ketamine administration produces antidepressant-like
response especially in treatmentresistant depression patients. Ketamine's rapid and …

Intraoperative ketamine for reduction in postpartum depressive symptoms after cesarean delivery: A double‐blind, randomized clinical trial

J Yao, T Song, Y Zhang, N Guo, P Zhao - Brain and behavior, 2020 - Wiley Online Library
Background Postpartum depression (PPD) is a common mental disease happens in
perinatal period. Ketamine as an anesthesia and analgesia drug has been used for a long …

A single dose of S‐ketamine induces long‐term antidepressant effects and decreases oxidative stress in adulthood rats following maternal deprivation

GZ Reus, AS Carlessi, SE Titus… - Developmental …, 2015 - Wiley Online Library
Ketamine, an antagonist of N‐methyl‐d‐aspartate receptors, has produced rapid
antidepressant effects in patients with depression, as well as in animal models. However …

[HTML][HTML] The effect of ketamine on preventing postpartum depression

M Alipoor, M Loripoor, M Kazemi… - Journal of medicine …, 2021 - ncbi.nlm.nih.gov
Postpartum depression is a common disabling psychosocial disorder that could have
adverse effects on the life of the mother, infant, and family. The present study was conducted …

Exploring perinatal ketamine for postpartum depression following cesarean section: A systematic review

J Thompson, DF Lo, A Foschini… - Psychiatry and Clinical …, 2024 - Wiley Online Library
The aim of this study was to explore the use of perinatal ketamine to see if it can be used for
the reduction of postpartum depression (PPD) following cesarean section (C‐section) …

[PDF][PDF] Chronic administration of ketamine ameliorates the anxiety-and aggressive-like behavior in adolescent mice induced by neonatal maternal separation

SY Shin, NJ Baek, SH Han… - The Korean Journal of …, 2019 - synapse.koreamed.org
Ketamine has long been used as an anesthetic agent. However, ketamine use is associated
with numerous side effects, including flashbacks, amnesia, delirium, and aggressive or …

[HTML][HTML] Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats

Z Ren, M Wang, M Aldhabi, R Zhang, Y Liu, S Liu… - Neurobiology of …, 2022 - Elsevier
Rapid antidepressant effects of S-ketamine have repeatedly been confirmed in patients with
depression, as well as in chronic unpredictable mild stress (CUMS) animal models …

[HTML][HTML] Exploring the Efficacy of Ketamine as an Anesthetic and Antidepressant in Postpartum Depression: A Case Study Analysis

C Benjamin, RT Atalay, O Kolawole, M Ramallo… - Cureus, 2024 - ncbi.nlm.nih.gov
Postpartum depression is a common mental health disorder that affects women within six
months after giving birth. It is characterized by sadness, anxiety, and extreme fatigue, which …