[HTML][HTML] Alterations of sphingolipid metabolism in different types of polycystic ovary syndrome
J Li, LM Xie, JL Song, LF Yau, JN Mi, CR Zhang… - Scientific Reports, 2019 - nature.com
The roles of sphingolipids in polycystic ovary syndrome (PCOS) are still unknown. This study
aimed to investigate the sphingolipid characteristics for different types of PCOS using liquid …
aimed to investigate the sphingolipid characteristics for different types of PCOS using liquid …
[HTML][HTML] Identification of a specific plasma sphingolipid profile in a group of normal-weight and obese subjects: a novel approach for a “biochemical” diagnosis of …
AE Rigamonti, M Dei Cas, D Caroli, A De Col… - International Journal of …, 2023 - mdpi.com
Metabolic syndrome is nosographically defined by using clinical diagnostic criteria such as
those of the International Diabetes Federation (IDF) ones, including visceral adiposity, blood …
those of the International Diabetes Federation (IDF) ones, including visceral adiposity, blood …
[HTML][HTML] Blood sphingolipidomics in healthy humans: impact of sample collection methodology
SM Hammad, JS Pierce, F Soodavar, KJ Smith… - Journal of lipid …, 2010 - ASBMB
We used a HPLC-MS/MS methodology for determination of a basic metabolomic profile (18:
1, 18: 0 sphingoid backbone, C 14-C 26 N-acyl part) of" normal" sphingolipid levels in …
1, 18: 0 sphingoid backbone, C 14-C 26 N-acyl part) of" normal" sphingolipid levels in …
[HTML][HTML] Effects of pregnancy on plasma sphingolipids using a metabolomic and quantitative analysis approach
Changes in the maternal metabolome, and specifically the maternal lipidome, that occur
during pregnancy are relatively unknown. The objective of this investigation was to evaluate …
during pregnancy are relatively unknown. The objective of this investigation was to evaluate …
Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics
Y Jiang, J Qi, X Xue, R Huang, J Zheng… - Gynecological …, 2020 - Taylor & Francis
This study aimed to identify potential lipid biomarkers in women with polycystic ovary
syndrome (PCOS) and determine their predictive value for PCOS. Eighteen women with …
syndrome (PCOS) and determine their predictive value for PCOS. Eighteen women with …
[HTML][HTML] Development of an advanced liquid chromatography–tandem mass spectrometry measurement system for simultaneous sphingolipid analysis
B Uranbileg, E Sakai, M Kubota, H Isago, M Sumitani… - Scientific Reports, 2024 - nature.com
Mass spectrometry-based lipidomics approaches offer valuable tools for the detection and
quantification of various lipid species, including sphingolipids. The present study aimed to …
quantification of various lipid species, including sphingolipids. The present study aimed to …
[HTML][HTML] Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome
M Jové, I Pradas, A Naudí, S Rovira-Llopis, C Bañuls… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Purpose In this work, a non-targeted approach was used to unravel changes in the plasma
lipidome of PCOS patients. The aim is to offer new insights in PCOS patients strictly selected …
lipidome of PCOS patients. The aim is to offer new insights in PCOS patients strictly selected …
Characterizing plasma phospholipid fatty acid profiles of polycystic ovary syndrome patients with and without insulin resistance using GC–MS and chemometrics …
XJ Zhang, LL Huang, H Su, YX Chen, J Huang… - … of pharmaceutical and …, 2014 - Elsevier
Polycystic ovary syndrome (PCOS), a heterogeneous endocrine and metabolic disorder, is
the leading cause of infertility in women of reproductive age. Insulin resistance (IR) occurs in …
the leading cause of infertility in women of reproductive age. Insulin resistance (IR) occurs in …
[HTML][HTML] Circulating sphingolipids and glucose homeostasis: an update
S Ali-Berrada, J Guitton, S Tan-Chen… - International Journal of …, 2023 - mdpi.com
Sphingolipids are a family of lipid molecules produced through different pathways in
mammals. Sphingolipids are structural components of membranes, but in response to …
mammals. Sphingolipids are structural components of membranes, but in response to …
[HTML][HTML] Sphingolipids in obesity and correlated co-morbidities: the contribution of gender, age and environment
E Torretta, P Barbacini, NM Al-Daghri… - International Journal of …, 2019 - mdpi.com
This paper reviews our present knowledge on the contribution of ceramide (Cer),
sphingomyelin (SM), dihydroceramide (DhCer) and sphingosine-1-phosphate (S1P) in …
sphingomyelin (SM), dihydroceramide (DhCer) and sphingosine-1-phosphate (S1P) in …