Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …

Globally, cancer is amongst the most deadly diseases due to the low efficiency of the
conventional and obsolete chemotherapeutic methodologies and their many downsides …

Nanocarriers as drug delivery systems are promising and becoming popular, especially for
cancer treatment. In addition to improving the pharmacokinetics of poorly soluble …

There are two main mechanisms by which cells become multidrug resistant (MDR): by
increasing drug efflux pumps on the cell membrane and by increasing anti-apoptotic …

Because of the complexity of cancer, combination therapy is becoming increasingly
important to overcome multidrug resistance in cancer and to enhance apoptosis. Cancer …

The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug
resistance of tumor cells, which is usually caused by abnormal gene expression. RNA …

RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …

The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …

Nanomedicine is a growing research field dealing with the creation and manipulation of
materials at a nanometer scale for the better treatment, diagnosis and imaging of diseases …

Introduction: Cancer is the leading cause of death worldwide. Current cancer treatments in
the clinic mainly include chemotherapy, radiotherapy and surgery, with chemotherapy being …