Glioma cell density in a rat gene therapy model gauged by water relaxation rate along a fictitious magnetic field
Longitudinal and transverse rotating‐frame relaxation time constants, T1ρ and T2ρ, have
previously been successfully applied to detect gene therapy responses and acute stroke in …
previously been successfully applied to detect gene therapy responses and acute stroke in …
Low Spin-Lock Field T1 Relaxation in the Rotating Frame as a Sensitive MR Imaging Marker for Gene Therapy Treatment Response in Rat Glioma1
Purpose: To prospectively assess the effectiveness of T1 relaxation in the rotating frame
(T1ρ) dispersion and the low spin-lock radiofrequency field (B1) T1ρ magnetic resonance …
(T1ρ) dispersion and the low spin-lock radiofrequency field (B1) T1ρ magnetic resonance …
Water spin dynamics during apoptotic cell death in glioma gene therapy probed by T1ρ and T2ρ
A Sierra, S Michaeli, JP Niskanen… - … in Medicine: An …, 2008 - Wiley Online Library
Longitudinal and transverse relaxations in the rotating frame, with characteristic time
constants T1ρ and T2ρ, respectively, have potential to provide unique MRI contrast in vivo …
constants T1ρ and T2ρ, respectively, have potential to provide unique MRI contrast in vivo …
Role of transmembrane water exchange in glioma invasion/migration: in vivo preclinical study by relaxometry at very low magnetic field
MR Ruggiero, H Ait Itto, S Baroni, S Pierre, J Boutonnat… - Cancers, 2022 - mdpi.com
Simple Summary Since the pioneering work of Damadian (1971), the longitudinal T1-
relaxation of nuclear magnetic resonance (NMR) has been reported to generate significant …
relaxation of nuclear magnetic resonance (NMR) has been reported to generate significant …
MRI contrast from relaxation along a fictitious field (RAFF)
T Liimatainen, DJ Sorce, R O'Connell… - Magnetic resonance …, 2010 - Wiley Online Library
A new method to measure rotating frame relaxation and to create contrast for MRI is
introduced. The technique exploits relaxation along a fictitious field (RAFF) generated by …
introduced. The technique exploits relaxation along a fictitious field (RAFF) generated by …
Functional diffusion map: a noninvasive MRI biomarker for early stratification of clinical brain tumor response
BA Moffat, TL Chenevert… - Proceedings of the …, 2005 - National Acad Sciences
Assessment of radiation and chemotherapy efficacy for brain cancer patients is traditionally
accomplished by measuring changes in tumor size several months after therapy has been …
accomplished by measuring changes in tumor size several months after therapy has been …
Water diffusion in a rat glioma during ganciclovir‐thymidine kinase gene therapy‐induced programmed cell death in vivo: correlation with cell density
PK Valonen, KK Lehtimäki, TH Väisänen… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To study the characteristics of diffusion magnetic resonance imaging (MRI) contrast
in a rat brain BT4C glioma during progression of ganciclovir (GCV)‐thymidine kinase gene …
in a rat brain BT4C glioma during progression of ganciclovir (GCV)‐thymidine kinase gene …
Quantification of water diffusion and relaxation times of human U87 tumors in a mouse model
Y Sun, RV Mulkern, K Schmidt, S Doshi… - NMR in …, 2004 - Wiley Online Library
Assessing the potential of anti‐cancer agents can be greatly facilitated by applying MRI
methods to investigations with animal models. Quantitative diffusion imaging, T1, and T2 …
methods to investigations with animal models. Quantitative diffusion imaging, T1, and T2 …
Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors
Background: A surrogate marker for treatment response that can be observed earlier than
comparison of sequential magnetic resonance imaging (MRI) scans, which depends on …
comparison of sequential magnetic resonance imaging (MRI) scans, which depends on …
Earlier detection of tumor treatment response using magnetic resonance diffusion imaging with oscillating gradients
DC Colvin, ME Loveless, MD Does, Z Yue… - Magnetic resonance …, 2011 - Elsevier
An improved method for detecting early changes in tumors in response to treatment, based
on a modification of diffusion-weighted magnetic resonance imaging, has been …
on a modification of diffusion-weighted magnetic resonance imaging, has been …