Opioids are an important therapeutic option for severe resistant chronic pain but, in the
absence of proper oversight, their use has risks. The level of prescription opioid …

Background: The non-medical use of and harms related to prescription opioid (PO)
analgesics–key medications to treat severe and chronic pain-are an emerging public health …

In the the past two decades the medical use of prescription opioids (POs), in particular
oxycodone, increased up to 14-fold in the US and Canada. The high consumption of these …

An increase in the prescribing of opioids over the past several years often has been
perceived as the primary reason for the increase in the nonmedical use of prescription …

Opioid use in chronic pain treatment is complex, as patients may derive both benefit and
harm. Identification of individuals currently using opioids in a problematic way is important …

The number of opioid prescriptions has increased significantly over the last few years due to
multiple factors, such as physicians' heightened attention to pain management, greater …

Nearly four years after the United States Congress heralded a “decade of pain control and
research”, chronic pain remains a mounting public health concern worldwide. The …

Objective Sharp increases in opioid prescriptions, and associated increases in overdose
deaths in the 2000s, evoked widespread calls to change perceptions of opioid analgesics …

Background: Canada has featured the second-highest levels of prescription opioid (PO) use
globally behind the United States, and reported extensive PO-related harms (eg, non …

Abstract In the United States, opioid analgesics have increasingly been prescribed in the
treatment of chronic pain, and this trend has accompanied increasing rates of misuse and …