Functional gene polymorphisms in aggressive and chronic periodontitis

PM Brett, P Zygogianni, GS Griffiths… - Journal of dental …, 2005 - journals.sagepub.com
There is strong evidence that genetic as well as environmental factors affect the
development of periodontitis, and some suggestion that aggressive and chronic forms of the …

Genetic susceptibility to periodontitis

ML Laine, W Crielaard, BG Loos - Periodontology 2000, 2012 - Wiley Online Library
In this systematic review, we explore and summarize the peer‐reviewed literature on
putative genetic risk factors for susceptibility to aggressive and chronic periodontitis. A …

Gene polymorphisms in chronic periodontitis

ML Laine, BG Loos, W Crielaard - International journal of …, 2010 - Wiley Online Library
We aimed to conduct a review of the literature for gene polymorphisms associated with
chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English …

Genetic variations in cytokine expression: a risk factor for severity of adult periodontitis

KS Kornman, FS di Giovine - Annals of Periodontology, 1998 - Wiley Online Library
Periodontitis is a collection of chronic inflammatory diseases that are caused by specific
bacteria. The bacteria activate inflammatory mechanisms in the periodontal tissues that …

The interleukin‐1 genotype as a severity factor in adult periodontal disease

KS Kornman, A Crane, HY Wang… - Journal of clinical …, 1997 - Wiley Online Library
Although specific bacteria, dental plaque, and age are associated with periodontal disease,
there are currently no reliable predictors of periodontitis severity. Studies in twins have …

Single‐nucleotide polymorphisms in the IL‐4 and IL‐13 promoter region in aggressive periodontitis

JR Gonzales, M Mann, J Stelzig… - Journal of clinical …, 2007 - Wiley Online Library
Abstract Introduction: IL‐4 and IL‐13 polymorphisms have been shown to influence the
susceptibility to systemic diseases. In this study, possible associations between the IL‐4 …

Linkage disequilibrium of interleukin‐1 genetic polymorphisms with early‐onset periodontitis

SR Diehl, YF Wang, CN Brooks… - Journal of …, 1999 - Wiley Online Library
Background: Genetic polymorphisms at interleukin (IL)‐1α and IL‐1β were recently
suggested to be associated with severity of adult periodontitis. We evaluated whether these …

Association of interleukin‐1 gene variations with moderate to severe chronic periodontitis in multiple ethnicities

X Wu, S Offenbacher, NJ Lόpez, D Chen… - Journal of …, 2015 - Wiley Online Library
Background and Objective Genetic markers associated with disease are often non‐
functional and generally tag one or more functional “causative” variants in linkage …

Role of genetic factors in the pathogenesis of aggressive periodontitis

AR Vieira, JM Albandar - Periodontology 2000, 2014 - Wiley Online Library
This article critically reviews the evidence for a role of genetic factors in the pathogenesis of
aggressive periodontitis and discusses the study approaches commonly used to identify …

Association of interleukin‐1 gene polymorphisms with early‐onset periodontitis

JM Parkhill, BJW Hennig, ILC Chapple… - Journal of Clinical …, 2000 - Wiley Online Library
Background, aims: Early onset periodontal diseases (EOP) are a group of inflammatory
disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals …