Whole mixture-based testing using in vitro new approach methodologies (NAMs) has been
suggested to facilitate the hazard and risk assessment of complex environmental mixtures …

Complex mixtures of polycyclic aromatic hydrocarbons (PAHs) are common environmental
pollutants associated with adverse human health effects including cancer. However, the risk …

Estimating cancer risk from environmental mixtures containing polycyclic aromatic
hydrocarbons (PAHs) is challenging. Ideally, each mixture would undergo toxicity testing to …

In order to compare a standard chemical-based risk assessment with in vitro genotoxicity
assays, two complex environmental mixtures from a wood-preserving site were analyzed in …

Human exposures to polycyclic aromatic hydrocarbon (PAH) occur in complex mixtures.
Here, gene expression patterns were investigated using standard reference material (SRM) …

Many of the toxic and carcinogenic effects of urban air pollution have been linked to
polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate matter (PM). The …

Concentrations of 34 unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs
and Me-PAHs) and AhR-mediated activities in settled dust samples were determined by a …

This study evaluates the risk assessment approach currently employed for polycyclic
aromatic hydrocarbon (PAH)-contaminated media, wherein carcinogenic hazards are …

In this review we discuss the effects of exposure to complex PAH mixtures in vitro and in vivo
on mechanisms related to carcinogenesis. Of particular concern regarding exposure to …

The polycyclic aromatic hydrocarbons (PAHs) benzo [a] pyrene (B [a] P) and dibenzo [a, l]
pyrene (DB [a, l] P) are well-studied environmental carcinogens, however, their potency …