[HTML][HTML] Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study
SG Snowden, AA Ebshiana, A Hye, Y An… - PLoS …, 2017 - journals.plos.org
Background The metabolic basis of Alzheimer disease (AD) pathology and expression of AD
symptoms is poorly understood. Omega-3 and-6 fatty acids have previously been linked to …
symptoms is poorly understood. Omega-3 and-6 fatty acids have previously been linked to …
Blood fatty acids in Alzheimer's disease and mild cognitive impairment: A meta-analysis and systematic review
Plasma fatty acids have been reported to be dysregulated in mild cognitive impairment (MCI)
and Alzheimer's disease (AD), though outcomes are not always consistent, and subject …
and Alzheimer's disease (AD), though outcomes are not always consistent, and subject …
Plasma and brain fatty acid profiles in mild cognitive impairment and Alzheimer's disease
SC Cunnane, JA Schneider, C Tangney… - Journal of …, 2012 - content.iospress.com
Alzheimer's disease (AD) is generally associated with lower omega-3 fatty acid intake from
fish but despite numerous studies, it is still unclear whether there are differences in omega-3 …
fish but despite numerous studies, it is still unclear whether there are differences in omega-3 …
Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis
The development of Alzheimer's dementia (AD) accompanies both central and peripheral
metabolic disturbance, but the metabolic basis underlying AD and metabolic markers …
metabolic disturbance, but the metabolic basis underlying AD and metabolic markers …
[HTML][HTML] Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease
The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic
approach to identify lipid abnormalities in the brains of subjects with AD (N= 37) compared …
approach to identify lipid abnormalities in the brains of subjects with AD (N= 37) compared …
Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease
DC Wang, CH Sun, LY Liu, XH Sun, XW Jin… - Neurobiology of …, 2012 - Elsevier
Previous studies showed the relationship between fatty acids and the risk of developing
Alzheimer's disease (AD). However, they did not address potential differences in free fatty …
Alzheimer's disease (AD). However, they did not address potential differences in free fatty …
Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease
T Fraser, H Tayler, S Love - Neurochemical research, 2010 - Springer
Dietary ω3-polyunsaturated fatty acids are thought to influence the risk of Alzheimer's
disease (AD), and supplemental docosahexaenoic acid (DHA; 22: 6n-3) has been reported …
disease (AD), and supplemental docosahexaenoic acid (DHA; 22: 6n-3) has been reported …
Medium-chain triglycerides improved cognition and lipid metabolomics in mild to moderate Alzheimer's disease patients with APOE4−/−: a double-blind, randomized …
Q Xu, Y Zhang, X Zhang, L Liu, B Zhou, R Mo, Y Li, H Li… - Clinical Nutrition, 2020 - Elsevier
Background Previous clinical and animal studies suggested that medium-chain triglycerides
(MCT) might be an alternative energy substrate for the brain and might benefit patients with …
(MCT) might be an alternative energy substrate for the brain and might benefit patients with …
Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe
Objective: The long-chain ω-3 fatty acids eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) are potential candidates for interventions to delay Alzheimer …
docosahexaenoic acid (DHA) are potential candidates for interventions to delay Alzheimer …
[HTML][HTML] Human cerebrospinal fluid fatty acid levels differ between supernatant fluid and brain-derived nanoparticle fractions, and are altered in Alzheimer's disease
AN Fonteh, M Cipolla, J Chiang, X Arakaki… - PloS one, 2014 - journals.plos.org
Background Although saturated (SAFA), monounsaturated (MUFA), and polyunsaturated
(PUFA) fatty acids are important structural components of neuronal membranes and …
(PUFA) fatty acids are important structural components of neuronal membranes and …