Centromeres are essential for chromosome inheritance and genome stability. Centromeric
proteins, including the centromeric histone centromere protein A (CENP-A), define the site of …

Centromeres are specified by sequence-independent epigenetic mechanisms in most
organisms. Rarely, centromere repositioning results in neocentromere formation at ectopic …

Human centromeres form primarily on α-satellite DNA but sporadically arise de novo at
naive ectopic loci, creating neocentromeres. Centromere inheritance is driven primarily by …

The duplication and segregation of the genome during cell division is crucial to maintain cell
identity, development of organisms and tissue maintenance. Centromeres are at the basis of …

Centromeres are essential to genome inheritance, serving as the site of kinetochore
assembly and coordinating chromosome segregation during cell division. Abnormal …

The centromere serves as the control locus for chromosome segregation at mitosis and
meiosis. In most eukaryotes, including mammals, the location of the centromere is …

The centromere is an important genomic locus for chromosomal segregation. Although the
centromere is specified by sequence-independent epigenetic mechanisms in most …

Centromeres are specialized chromosomal regions that recruit kinetochore proteins and
mediate spindle microtubule attachment to ensure faithful chromosome segregation during …

Centromeres represent the final frontier of eukaryotic genomes. Although they are defining
features of chromosomes—the points at which spindle microtubules attach—the …

The centromere is a complex chromosomal locus where the kinetochore is formed and
microtubules attach during cell division. Centromere identity involves both genomic and …