Objective Worldwide, the highest frequencies of APOL 1‐associated kidney variants are
found in indigenous West Africans among whom small vessel disease (SVD) ischemic …

Ischaemic stroke is a heterogeneous multifactorial disorder. Epidemiological data provide
substantial evidence for a genetic component to the disease, but the extent of predisposition …

Abstract The histone deacetylase 9 (HDAC9) polymorphism rs2107595 is associated with
an increased risk for large vessel atherosclerotic stroke (LVAS). In humans, there remains a …

Recently, a genome-wide association study (GWAS) detected two histone deacetylase 9
(HDAC9) polymorphisms (rs2074633 and rs28688791) which may be associated with risk of …

Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …

Background and Purpose—Recent evidence has implicated the genes for 5-lipoxygenase
activating protein (ALOX5AP) and phosphodiesterase 4D (PDE4D) as susceptibility genes …

Background: The extent to which genetic effects on the different subtypes of small (SVD) and
large vessel disease (LVD) ischaemic stroke differ remains controversial. Methods: A …

Introduction: The aim of this project was to assess the prevalence of four selected SNPs
rs4977574 and rs7857345 (CDKN2B-AS1 gene) and rs3798220 and rs10455872 …

Stroke is a multifactorial disease responsible for nearly 10% of deaths each year in
industrialized countries. While some monogenic forms of stroke have been described, the …

Objective: To determine whether common variants in familial cerebral small vessel disease
(SVD) genes confer risk of sporadic cerebral SVD. Methods: We meta-analyzed genotype …