Daytime napping is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …

Aims Sleep disorders are associated with an increased risk of cardiometabolic diseases in
observational studies, but the causality remains unclear. In this study, we leveraged two …

Importance Obesity is a growing public health threat leading to serious health
consequences. Late bedtime and sleep loss are common in modern society, but their …

Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated
with substantial functional deficits. Here, we identify 42 loci for self-reported daytime …

Associations between night sleep duration and cardiovascular risk factors in adults have
been well documented. However, the associations for daytime napping remain unclear. In …

Sleep is an essential state of decreased activity and alertness but molecular factors
regulating sleep duration remain unknown. Through genome-wide association analysis in …

Considerable recent advancements in elucidating the genetic architecture of sleep traits and
sleep disorders may provide insight into the relationship between sleep and obesity. Despite …

Chronic sleep disturbances, associated with cardiometabolic diseases, psychiatric disorders
and all-cause mortality,, affect 25–30% of adults worldwide. Although environmental factors …

Background Numerous studies suggest genetic influences on sleepiness and circadian
rhythms. The Sleep Heart Health Study collected questionnaire data on sleep habits and …

Excessive daytime sleepiness (EDS) is classically viewed as a consequence of insufficient
sleep or a symptom of sleep disorders. Epidemiological and clinical evidence have shown …