Immune responses and therapeutic options in psoriasis

IS Afonina, E Van Nuffel, R Beyaert - Cellular and Molecular Life Sciences, 2021 - Springer
Psoriasis is a chronic inflammatory disease of the skin that affects about 2–3% of the
population and greatly impairs the quality of life of affected individuals. Psoriatic skin is …

Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders

LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …

Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

The interplay between keratinocytes and immune cells in the pathogenesis of psoriasis

C Albanesi, S Madonna, P Gisondi… - Frontiers in …, 2018 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease resulting from genetic, epigenetic,
environmental, and lifestyle factors. To date, several immunopathogenic mechanisms of …

Psoriasis: what we have learned from mouse models

EF Wagner, HB Schonthaler… - Nature Reviews …, 2010 - nature.com
Psoriasis is a common inflammatory skin disease of unknown etiology, for which there is no
cure. This heterogeneous, cutaneous, inflammatory disorder is clinically characterized by …

[HTML][HTML] New frontiers in psoriatic disease research, part I: genetics, environmental triggers, immunology, pathophysiology, and precision medicine

D Yan, JE Gudjonsson, S Le, E Maverakis… - Journal of Investigative …, 2021 - Elsevier
Psoriasis is a chronic inflammatory condition characterized by systemic immune
dysregulation. Over the past several years, advances in genetics, microbiology …

Immunopathogenesis of psoriasis

P Di Meglio, FO Nestle - Clinical and basic immunodermatology, 2017 - Springer
Psoriasis is a common, complex, inflammatory skin disease resulting from the interplay of
genetic, environmental and immunological factors. In the last four decades, advances in …

Immunology of psoriasis

C Albanesi - Clinical immunology, 2019 - Elsevier
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. There is a wide spectrum of cutaneous …

Cellular mechanisms of psoriasis pathogenesis: a systemic review

M Wu, C Dai, F Zeng - Clinical, cosmetic and investigational …, 2023 - Taylor & Francis
Psoriasis is a common inflammatory skin disease characterized by abnormal proliferation of
epidermal keratinocytes and massive infiltration of inflammatory cells. Many kinds of cells …

Mouse models of psoriasis and their relevance

K Nakajima, S Sano - The Journal of Dermatology, 2018 - Wiley Online Library
Psoriasis is an inflammatory skin disorder that includes dynamic interactions between the
immune system and skin and is clinically characterized by keratinocyte proliferation and …