Adolescents and young adults with cancer: the scope of the problem and criticality of clinical trials

A Bleyer, T Budd, M Montello - … International Journal of the …, 2006 - Wiley Online Library
In the US, older adolescents and young adults with cancer have benefited less from
therapeutic advances than did either younger or older patients. One factor that may explain …

The challenges of clinical trials for adolescents and young adults with cancer

A Ferrari, M Montello, T Budd… - Pediatric blood & …, 2008 - Wiley Online Library
Abstract In the United States, Europe, and Australia, and probably all countries of the world,
older adolescents and young adults with cancer are under‐represented in clinical trials of …

[引用][C] Overview of adolescent and young adult oncology

PF Coccia - Journal of Oncology Practice, 2019 - ascopubs.org
In 1996, W. Archie Bleyer made the seminal observation that adolescents, age 15 to 19
years, had not benefited from cancer therapy improvements to the same extent as children …

Recruitment of adolescents and young adults to cancer clinical trials—international comparisons, barriers, and implications

LA Fern, JS Whelan - Seminars in oncology, 2010 - Elsevier
The last 30 years have seen significant improvements in survival rates for children and older
adults. In contrast, the 5-year survival rate among 20 to 39 year olds has been static at …

Cancer in older adolescents and young adults: epidemiology, diagnosis, treatment, survival, and importance of clinical trials

WA Bleyer - Medical and Pediatric Oncology: The Official …, 2002 - Wiley Online Library
Cancer in adolescents and young adults has unique features in addition to the special
medical, physical, psychological, and social needs of patients in this age group. The …

Participation of adolescents with cancer in clinical trials

A Ferrari, A Bleyer - Cancer treatment reviews, 2007 - Elsevier
Adolescent patients with cancer reside in a “no-man's land” between the world of pediatric
oncology and that of “adult” medical oncology. As compared to younger and older patients …

National cancer clinical trials: children have equal access; adolescents do not

WA Bleyer, H Tejeda, SB Murphy, LL Robison… - Journal of Adolescent …, 1997 - Elsevier
PURPOSE.: To determine whether adolescents with cancer, who in comparison to younger
patients have a higher cancer incidence and lower mortality reduction, have equal access to …

Challenges in the recruitment of adolescents and young adults to cancer clinical trials

ME Burke, K Albritton, N Marina - … International Journal of the …, 2007 - Wiley Online Library
The adolescent and young adult (AYA) oncology population has seen inferior progress in
cancer survival compared with younger children and older adults over the past 25 years …

Adolescent and young adult (AYA) oncology: the first A

A Bleyer - Pediatric hematology and oncology, 2007 - Taylor & Francis
Whereas adolescents with cancer as a group used to have a better prognosis than children
with malignant disease, trends suggest that the overall survival of 15-to 19-year-olds is now …

Role of clinical trials in survival progress of American adolescents and young adults with cancer—and lack thereof

A Bleyer, E Tai, S Siegel - Pediatric blood & cancer, 2018 - Wiley Online Library
Abstract In the United States, adolescent and young adult (AYA) patients with cancer have
the lowest clinical trial participation rate of all age groups and slower progress in survival …