Background White matter hyperintensities (WMH) are frequently found in Alzheimer's
disease (AD). Commonly considered as a marker of cerebrovascular disease, regional …

Introduction White matter hyperintensities (WMH) are often described in Alzheimer's disease
(AD), but their topography and specific relationships with cognition remain unclear. Methods …

Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …

Background To promote the development of effective therapies, there is an important need
to characterize the full spectrum of neuropathological changes associated with Alzheimer's …

Introduction Cognitive tests and nonamyloid imaging biomarkers do not consistently identify
preclinical AD. The objective of this study was to evaluate whether white matter …

Introduction We sought to investigate associations of regional white matter hyperintensities
(WMHs) within white matter (WM) tracts with cardiovascular risk and brain aging-related …

Background and Objectives White matter hyperintensities (WMH) correlate with Alzheimer
disease (AD) biomarkers cross-sectionally and modulate AD pathogenesis. Longitudinal …

Background/Objective: Higher white matter hyperintensity (WMH) load has been reported in
Alzheimer's disease (AD) patients in different brain regions when compared to controls. We …

Accumulating evidence implicates small vessel cerebrovascular disease, visualized as
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …

Background White matter hyperintensities (WMH) of presumed vascular origin have been
associated with an increased risk of Alzheimer's disease (AD). This study aims to describe …