INTRODUCTION: Vitamin D deficiency has been linked to type 1 and 2 diabetes, whereas
supplementation may prevent both diseases. However, the extent of the effects of vitamin D …

Background Studies have shown that vitamin D can enhance glucose-stimulated insulin
secretion (GSIS) and change the expression of genes in pancreatic β-cells. Still the …

Protection against insulitis and diabetes by active vitamin D, 1, 25-dihydroxyvitamin D3 (1,
25 (OH) 2D3), in nonobese diabetic mice has until now mainly been attributed to its …

Dihydroxyvitamin D3 (1, 25-(OH) 2D3) is an immune modulator that prevents experimental
autoimmune diseases. Receptors for 1, 25-(OH) 2D3 are present in pancreatic β-cells, the …

Aim Vitamin D deficiency in rodents negatively affects glucose-stimulated insulin secretion
(GSIS) and human epidemiological studies connect poor vitamin D status with type 2 …

Background Vitamin D affects the pancreatic beta cell function and in vitro studies have
shown that vitamin D may influence insulin secretion, apoptosis, and gene regulation …

Previous studies have indicated that the pancreas has receptors specific for 1, 25-
dihydroxyvitamin D3 [1, 25-(OH) 2D3] and that 1, 25-(OH) 2D3 increases insulin secretion in …

Vitamin D deficiency is associated with beta-cell dysfunction and a higher risk of diabetes,
but mice and humans with an absence of the vitamin D receptor (VDR) display normal …

A number of studies have suggested that Vitamin D has a potential role in the development/
treatment of diabetes. These effects may be mediated by circulating levels of 1α, 25 (OH) …

Background: The immunomodulatory role of 1, 25-Dihydroxy vitamin D3 (1, 25 (OH) 2D3) is
exerted through its interaction with the vitamin D receptor (VDR) present on pancreatic and …