[HTML][HTML] GRIK1 promotes glioblastoma malignancy and is a novel prognostic factor of poor prognosis
G Hou, X Xu, W Hu - Oncology Research, 2024 - ncbi.nlm.nih.gov
Primary tumors of the central nervous system (CNS) are classified into over 100 different
histological types. The most common type of glioma is derived from astrocytes, and the most …
histological types. The most common type of glioma is derived from astrocytes, and the most …
GRIK3: A novel oncogenic protein related to tumor TNM stage, lymph node metastasis, and poor prognosis of GC
B Gong, Y Li, Z Cheng, P Wang, L Luo… - Tumor …, 2017 - journals.sagepub.com
Glutamate receptor, ionotropic, kainate 3 (GRIK3), as a member of the glutamate kainate
receptor family, mainly participated in neuroactive ligand receptor interaction pathway. Other …
receptor family, mainly participated in neuroactive ligand receptor interaction pathway. Other …
[HTML][HTML] GRIK3 deficiency promotes non-small cell lung cancer progression by the regulation of the UBE2C/CDK1/Wnt signaling pathway
J Liu, ZX Zhao, BK Li, ZW Zhao - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Glutamate ionotropic receptor kainate type subunit 3 (GRIK3) is a predominant excitatory
neurotransmitter receptor in the mammalian brain. While it is known that GRIK3 is involved …
neurotransmitter receptor in the mammalian brain. While it is known that GRIK3 is involved …
GRIK5 stimulates colon cancer growth and metastasis through cAMP/PKA/CADM3 signaling
Z Xie, Y Ke, Z Li, J Chen, D Lei, G Chen… - Cell Biology …, 2023 - Wiley Online Library
Abstract Glutamate receptor, ionotropic, kainate 5 (GRIK5) is a member of glutamate
receptors participating, and the kainate receptor family has been proved to regulate cell …
receptors participating, and the kainate receptor family has been proved to regulate cell …
Overexpression of GRK3, promoting tumor proliferation, is predictive of poor prognosis in colon cancer
T Jiang, C Yang, L Ma, Z Wu, L Ye, X Ma, H Li… - Disease …, 2017 - Wiley Online Library
Deregulation of G protein‐coupled receptor kinase 3 (GRK3), which belongs to a subfamily
of kinases called GRKs, acts as a promoter mechanism in some cancer types. Our study …
of kinases called GRKs, acts as a promoter mechanism in some cancer types. Our study …
Glutamate receptor ionotropic, kainate 1 serves as a novel tumor suppressor of colorectal carcinoma and predicts clinical prognosis
Z Ren, J Liu, L Yao, J Li, Z Qi… - Experimental and …, 2020 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most malignant cancers worldwide. However, the
mechanisms of initiation and development of CRC are still largely unclear. The present …
mechanisms of initiation and development of CRC are still largely unclear. The present …
G-protein coupled receptor kinase (GRK)-5 regulates proliferation of glioblastoma-derived stem cells
Glioblastoma multiforme (GBM) is a grade IV malignant brain tumor with high mortality and
has been well known to involve many molecular pathways, including G-protein coupled …
has been well known to involve many molecular pathways, including G-protein coupled …
GRK5 functions as an oncogenic factor in non-small-cell lung cancer
LP Jiang, SQ Fan, QX Xiong, YC Zhou, ZZ Yang… - Cell Death & …, 2018 - nature.com
Lung cancer is the leading cause of cancer-related deaths worldwide, and non-small-cell
lung cancer (NSCLC) accounts for about 80% of all cases, which is the major subgroup of …
lung cancer (NSCLC) accounts for about 80% of all cases, which is the major subgroup of …
[HTML][HTML] GRK3 as a prognosis biomarker in gastric cancer
CL Fang, YF Tian, SS Lin, ST Hung, YC Hseu… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Globally, gastric cancer is ranked 4th and 3rd in terms of incidence and
mortality rate among all cancer types. This study aimed to examine the relationship between …
mortality rate among all cancer types. This study aimed to examine the relationship between …
[HTML][HTML] G protein-coupled receptor kinase 6 is overexpressed in glioma and promotes glioma cell proliferation
LQ Xu, SB Tan, S Huang, HY Ding, WG Li, Y Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The expression and potential biological functions of G protein-coupled receptor kinase 6
(GRK6) in human glioma are tested in this study. We show that protein and mRNA …
(GRK6) in human glioma are tested in this study. We show that protein and mRNA …