Transforming growth factor-β (TGFβ) family members are structurally and functionally related
cytokines that have diverse effects on the regulation of cell fate during embryonic …

Recent evidence continues to support a central role for TGFβ in tumor maintenance and
progression. Although this may involve TGFβ-mediated paracrine effects that modulate the …

Introduction: The transforming growth factor-β (TGF-β) signaling pathway has a pivotal role
in tumor suppression and yet, paradoxically, in tumor promotion. Functional context …

The transforming growth factor β (TGFβ) signaling pathway is a key player in metazoan
biology, and its misregulation can result in tumor development. The regulatory cytokine …

Transforming growth factor-β (TGFβ) is a ubiquitous cytokine essential for embryonic
development and postnatal tissue homeostasis. TGFβ signalling regulates several biological …

Transforming growth factor-β (TGF-β) regulates cell growth and differentiation, apoptosis,
cell motility, extracellular matrix production, angiogenesis, and cellular immunity. It has a …

Transforming growth factor‐beta (TGFβ) is a secreted cytokine, which intricately controls a
plethora of physiological and pathological processes during development and …

TGF-β is a ubiquitous cytokine that plays an active role in many cellular processes. Nearly
every cell type has the ability to secrete TGF-β, as well as the ability to respond to TGF-β via …

The transforming growth factor (TGF)-β signaling pathway is deregulated in many diseases,
including cancer. In healthy cells and early-stage cancer cells, this pathway has tumor …

The transforming growth factor‐β (TGF‐β) signalling pathway plays a critical and dual role in
the progression of human cancer. During the early phase of tumour progression, TGF‐β acts …